Evidence map›Paper›PMID 32245254›Full record

ReviewViruses2020

Fluorescence Microscopy of the HIV-1 Envelope.

Pablo Carravilla, José L Nieva, Christian Eggeling

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Pablo CarravillaInstitute of Applied Optics and Biophysics, Friedrich-Schiller-University Jena, Max-Wien Platz 1, 07743 Jena, Germany.ORCID 0000-0001-6592-7630
José L NievaDepartment of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain.
Christian EggelingInstitute of Applied Optics and Biophysics, Friedrich-Schiller-University Jena, Max-Wien Platz 1, 07743 Jena, Germany.
University of the Basque Country · ESLeibniz Institute of Photonic Technology · DE

Funding

Medical Research Council G0902418Medical Research Council MC_UU_00008/9Medical Research Council MC_UU_12010/9Medical Research Council MC_UU_12010/unit programmes G0902418Medical Research Council MC_UU_12025Medical Research Council MR/K01577X/1Wellcome Trust 098274/Z/12/ZWellcome Trust 100262Z/12/ZWellcome Trust 104924/14/Z/14Wellcome Trust Strategic Award 091911 (107457/Z/15/Z, Advanced Micron 299 Bioimaging Unit)
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) infection constitutes a major health and social issue worldwide. HIV infects cells by fusing its envelope with the target cell plasma membrane. This process is mediated by the viral Env glycoprotein and depends on the envelope lipid composition. Fluorescent microscopy has been employed to investigate the envelope properties, and the processes of viral assembly and fusion, but the application of this technique to the study of HIV is still limited by a number of factors, such as the small size of HIV virions or the difficulty to label the envelope components. Here, we review fluorescence imaging studies of the envelope lipids and proteins, focusing on labelling strategies and model systems.

Indexed as

Cell Membraneenv Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHumansLipidsMembrane LipidsMicroscopy, FluorescenceMolecular ConformationMolecular ImagingStructure-Activity RelationshipVirus AssemblyVirus InternalizationVirus Releaseenv Gene Products, Human Immunodeficiency VirusLipidsMembrane LipidsEnvenvelopefluorescenceHIVlipidmembranemicroscopysuper-resolution

Identifiers

PMID32245254
PMCPMC7150788
OpenAlexW3012376155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.