Evidence map›Paper›PMID 32245190›Full record

ArticlePharmaceutics2020

Topical Delivery of Meloxicam using Liposome and Microemulsion Formulation Approaches.

Julia Zhang, Anna Froelich, Bozena Michniak-Kohn

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Julia ZhangCenter for Dermal Research and Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Anna FroelichChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.ORCID 0000-0002-1491-1329
Bozena Michniak-KohnCenter for Dermal Research and Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Rutgers, The State University of New Jersey · USPoznan University of Medical Sciences · PL

Funding

European Union's Horizon 2020 research and innovation programme 778051Ministry of Science and Higher Education of Poland 3899/H2020/2018/2
6 · The paper itself

Abstract

The aim of this study is to develop, characterize and compare conventional liposome, deformable liposome (transfersome) and microemulsion formulations as potential topical delivery systems for meloxicam. Liposomes were characterized in terms of vesicle size, zeta potential and entrapment efficiency. For microemulsions, particle size, electrical conductivity and viscosity studies were performed to assess the structure of the investigated systems. An ex vivo skin permeation study has been conducted to compare these formulations. The dermal and transdermal delivery of meloxicam using these formulations can be a promising alternative to conventional oral delivery of non-steroidal anti-inflammatory drugs (NSAIDs) with enhanced local and systemic onset of action and reduced side effects.

Indexed as

ex vivo skin permeationliposomemeloxicammicroemulsiontransfersome

Identifiers

PMID32245190
PMCPMC7151031
OpenAlexW3010917557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.