Evidence map›Paper›PMID 32245170›Full record

ArticleNutrients2020

Neonatal Vitamin D Status and Risk of Asthma in Childhood: Results from the D-Tect Study.

Fanney Thorsteinsdottir, Isabel Cardoso, Amélie Keller, Maria Stougaard, Peder Frederiksen, Arieh Sierra Cohen, Ekaterina Maslova, Ramune Jacobsen, Vibeke Backer, Berit Lilienthal Heitmann

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06509776 (Early Life Determinants of Skeletal Maturation and Endocrine Health in Young Adults - A Nationwide Birth Cohort Study), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06509776 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Early Life Determinants of Skeletal Maturation and Endocrine Health in Young Adults - A Nationwide Birth Cohort Study

TypeobservationalSponsorHolbaek SygehusRan2024 to 2031Enrolled2,000ConditionsOsteoporosis, Sarcopenia, Obesity, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Vitamin DActa obstetricia et gynecologica Scandinavica · 2024
    Article
  10. Article
  11. Vitamin D and allergic diseases.Frontiers in immunology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Fetal Programming: Lung Health and Disease.Turkish thoracic journal · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Fanney ThorsteinsdottirResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.ORCID 0000-0002-3070-782X
Isabel CardosoResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.
Amélie KellerResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.
Maria StougaardResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.
Peder FrederiksenResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.
Arieh Sierra CohenDanish Center for Neonatal Screening, Department of Clinical Biochemistry and Immunology, Statens Serum Institute, 2300 Copenhagen, Denmark.ORCID 0000-0001-6410-7702
Ekaterina MaslovaDepartment of Primary Care and Public Health, Imperial College London, London W6 8RP, UK.ORCID 0000-0001-5415-8119
Ramune JacobsenDepartment of Pharmacy, University of Copenhagen, 2100 Denmark.
Vibeke BackerCenter for Physical Activity Research, Rigshospitalet and Copenhagen University, 2100 Copenhagen, Denmark.
Berit Lilienthal HeitmannResearch Unit for Dietary Studies, The Parker Institute, Bisbebjerg og Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.ORCID 0000-0002-6809-4504
Frederiksberg Hospital · DKStatens Serum Institut · DKUniversity of Copenhagen · DKCopenhagen University Hospital · DK

Funding

Danish Agency for Science and Higher Education 0603-00453BNovo Nordisk Fonden 2010-11-12 and 2009-07-28
6 · The paper itself

Abstract

backgroundlow vitamin D status in pregnancy can influence the offspring's lung function and contribute to childhood asthma development. The objective of this study was to examine the influence of neonatal vitamin D status on the development of asthma among children age 3-9 years in a large population sample.

methodin a case-cohort study utilizing a Danish biobank and register data we examined the association between neonatal 25-hydroxyvitamin D

resultsthe median 25(OH)D3 (interquartile range) for asthma cases was 23 nmol/L (14-35) and the sub-cohort 25 nmol/L (14-40). The hazard ratio for developing asthma between ages 3 and 9 years was lower for children in the fifth quintile of neonatal 25(OH)D

conclusionthe results from our study suggest that higher neonatal vitamin D concentration may reduce the risk of developing childhood asthma at ages 3-9 years, indicating that neonatal vitamin D status as a proxy of vitamin D status during the prenatal period is important for normal immune- and lung development.

Indexed as

Disease SusceptibilityAsthmaChildChild, PreschoolDenmarkDietary SupplementsFemaleHumansInfantInfant, NewbornMalePregnancyProportional Hazards ModelsPublic Health SurveillanceSeasonsVitamin DVitamin Dasthmachildhoodneonatalvitamin D

Identifiers

PMID32245170
PMCPMC7146263
OpenAlexW3012368097

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.