ArticleJournal of clinical medicine2020
Outcomes Associated with Respiratory Failure for Patients with Cardiogenic Shock and Acute Myocardial Infarction: A Substudy of the CULPRIT-SHOCK Trial.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Development and internal validation of an ICU mortality prediction model for patients with concurrent sepsis and heart failure: a retrospective cohort study based on eICU-CRD.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Clinical Profiles and Prognostic Patterns in Critically Ill Cardiac Patients Requiring Invasive Mechanical Ventilation: A Five-Year Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Acid-Base Status During Venoarterial Extracorporeal Membrane Oxygenator Support in Patients With Cardiogenic Shock.Journal of the American Heart Association · 2026Article
- Efficacy of Non-invasive Ventilation Compared with Invasive Mechanical Ventilation in Cardiogenic Shock: A Systematic Review and Meta-analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Experts' recommendations for the management of adult patients with cardiogenic shock.Annals of intensive care · 2026Article
- Respiratory Support and Mortality Risk Across the Spectrum of Cardiogenic Shock Severity.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Moving From the Epidemiology to the Treatment of Respiratory Failure in Patients With Cardiogenic Shock.JACC. Advances · 2025Article
- Ventilation strategies in cardiogenic shock: insights from the FRENSHOCK observational registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Observational
- Observational
- Ventilation strategies in cardiogenic shock: Insights from the AltShock-2 registry.European journal of heart failure · 2024Article
- Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units.JACC. Advances · 2024Article
- Stress Ulcer Prophylaxis in Mechanically Ventilated Patients With Acute Myocardial Infarction.JACC. Advances · 2024Article
- Rocuronium Versus Succinylcholine in Patients With Acute Myocardial Infarction Requiring Mechanical Ventilation.Journal of the American Heart Association · 2023Article
- Complicating Acute Myocardial Infarction. Current Status and Unresolved Targets for Subsequent Research.Journal of clinical medicine · 2021Review
- Prevalence of Noncardiac Multimorbidity in Patients Admitted to Two Cardiac Intensive Care Units and Their Association with Mortality.The American journal of medicine · 2021Observational
Corrections and comments
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Authors and funding
21 authors at 14 institutions in 9 countries.
Funding
Abstract
backgroundLittle is known about clinical outcomes of patients with acute myocardial infraction (AMI) complicated by cardiogenic shock (CS) requiring mechanical ventilation (MV). The aim of this study was to identify the characteristics, risk factors, and outcomes associated with the provision of MV in this specific high-risk population.
methodsPatients with CS complicating AMI and multivessel coronary artery disease from the CULPRIT-SHOCK trial were included. We explored 30 days of clinical outcomes in patients not requiring MV, those with MV on admission, and those in whom MV was initiated within the first day after admission.
resultsAmong 683 randomized patients included in the analysis, 17.4% received no MV, 59.7% were ventilated at admission and 22.8% received MV within or after the first day after admission. Patients requiring MV had a different risk-profile. Factors independently associated with the provision of MV on admission included higher body weight, resuscitation within 24 h before admission, elevated heart rate and evidence of triple vessel disease.
conclusionsRequiring MV in patients with CS complicating AMI is common and independently associated with mortality after adjusting for covariates. Patients with delayed MV initiation appear to be at higher risk of adverse outcomes. Further research is necessary to identify the optimal timing of MV in this high-risk population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.