Evidence map›Paper›PMID 32245092›Full record

ArticleInternational journal of molecular sciences2020

H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology.

Nan Han, Udo Jeschke, Christina Kuhn, Anna Hester, Bastian Czogalla, Sven Mahner, Miriam Rottmann, Doris Mayr, Elisa Schmoeckel, Fabian Trillsch

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nan HanDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.
Udo JeschkeDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.ORCID 0000-0003-2623-3235
Christina KuhnDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.
Anna HesterDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.
Bastian CzogallaDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.ORCID 0000-0001-6589-4736
Sven MahnerDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.
Miriam RottmannMunich Cancer Registry (MCR), Bavarian Cancer Registry-Regional Center Munich (LGL), Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Ludwig-Maximilians-University (LMU), 81377 Munich, Germany.
Doris MayrDepartment of Pathology, LMU Munich, Thalkirchner Str. 36, 80337 Munich, Germany.
Elisa SchmoeckelDepartment of Pathology, LMU Munich, Thalkirchner Str. 36, 80337 Munich, Germany.
Fabian TrillschDepartment of Obstetrics and Gynaecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.ORCID 0000-0002-1860-4350
LMU Klinikum · DELudwig-Maximilians-Universität München · DEUniversity Hospital Augsburg · DE

Funding

China Scholarship Council CSC
6 · The paper itself

Abstract

Posttranslational histone modification plays an important role in tumorigenesis. Histone modification is a dynamic response of chromatin to various signals, such as the exposure to calcitriol (1α,25(OH)

Indexed as

AdultAgedAged, 80 and overCalcitriolCell Line, TumorCell ProliferationEpigenesis, GeneticFemaleHistonesHumansKaplan-Meier EstimateLysineMethylationMiddle AgedMultivariate AnalysisOvarian NeoplasmsCalcitriolHistonesLysineReceptors, Calcitriol1α,25(OH)2D3calcitriolcell proliferationhistone 3 lysine 4 trimethylation (H3K4me3)histone modificationovarian cancerprognosisvitamin D receptor

Identifiers

PMID32245092
PMCPMC7139961
OpenAlexW3011986150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.