Evidence map›Paper›PMID 32245044›Full record

ArticleFoods (Basel, Switzerland)2020

Are Faba Bean and Pea Proteins Potential Whey Protein Substitutes in Infant Formulas? An In Vitro Dynamic Digestion Approach.

Linda Le Roux, Olivia Ménard, Raphaël Chacon, Didier Dupont, Romain Jeantet, Amélie Deglaire, Françoise Nau

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Human milkFrontiers in nutrition · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Current advances forFrontiers in nutrition · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linda Le RouxSill Dairy International, Raden, 29860 Plouvien, France.
Olivia MénardSTLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.
Raphaël ChaconSill Dairy International, Raden, 29860 Plouvien, France.
Didier DupontSTLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.ORCID 0000-0001-5304-6561
Romain JeantetSTLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.ORCID 0000-0001-5405-5056
Amélie DeglaireSTLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.
Françoise NauSTLO, INRAE, AGROCAMPUS OUEST, 35042 Rennes, France.ORCID 0000-0002-0167-8759

Funding

Association Nationale de la Recherche et de la Technologie 2016/0537
6 · The paper itself

Abstract

Infant formulas (IFs) are used as substitutes for human milk and are mostly based on cow milk proteins. For sustainability reasons, animal protein alternatives in food are increasingly being considered, as plant proteins offer interesting nutritional and functional benefits for the development of innovative IFs. This study aimed to assess how a partial substitution (50%) of dairy proteins with faba bean and pea proteins influenced the digestibility of IFs under simulated dynamic in vitro digestion, which were set up to mimic infant digestion. Pea- and faba bean-based IFs (PIF and FIF, respectively) have led to a faster aggregation than the reference milk-based IF (RIF) in the gastric compartment; that did not affect the digesta microstructure at the end of digestion. The extent of proteolysis was estimated via the hydrolysis degree, which was the highest for FIF (73%) and the lowest for RIF (50%). Finally, it was apparent that in vitro protein digestibility and protein digestibility-corrected amino acid score (PDCAAS)-like scores were similar for RIF and FIF (90% digestibility; 75% PDCAAS),

Indexed as

apparent protein digestibilityinfant formulain vitro digestionmicrostructureplant proteinproteolysis

Identifiers

PMID32245044
PMCPMC7142966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.