Evidence map›Paper›PMID 32244898›Full record

ArticleMolecules (Basel, Switzerland)2020

A2E Distribution in RPE Granules in Human Eyes.

Ziqiang Guan, Yiwen Li, Shuliang Jiao, Nusrat Yeasmin, Philip J Rosenfeld, Sander R Dubovy, Byron L Lam, Rong Wen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. iScience · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Protective Effects of Purple Corn (Preventive nutrition and food science · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ziqiang GuanDepartment of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-8082-3423
Yiwen LiBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Shuliang JiaoDepartment of Biomedical Engineering, Florida International University, Miami, FL 33174, USA.
Nusrat YeasminDepartment of Biomedical Engineering, Florida International University, Miami, FL 33174, USA.ORCID 0000-0002-2799-5701
Philip J RosenfeldBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Sander R DubovyBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Byron L LamBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Rong WenBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
University of Miami · USFlorida International University · USDuke Medical Center · US

Funding

STEROL LIPIDSU54GM069338 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 2003 to 2013
$72.2M
Imaging the functional biomarker of photoreceptorsR01EY026643 · NEI · FLORIDA INTERNATIONAL UNIVERSITY · PI JIAO, SHULIANG · 2017 to 2020
$1.9M
Hope For Vision Adrienne Arsht GrantNEI NIH HHS EY018586; EY026643; P30 EY14801NEI NIH HHS R01 EY026643NIGMS NIH HHS GM069338Research to Prevent Blindness 2015 Nelson Trust Award for Retinitis Pigmentosa to R.W.Research to Prevent Blindness Unrestricted grant to Bascom Palmer Eye Institute
6 · The paper itself

Abstract

A2E (

Indexed as

AgedAged, 80 and overCell FractionationChromatography, LiquidCytoplasmic GranulesFemaleFluorescent DyesHumansLipofuscinMaleRetinal Pigment EpitheliumRetinal PigmentsRetinoidsSpectrum AnalysisTandem Mass SpectrometryA2-E (N-retinylidene-N-retinylethanolamine)Fluorescent DyesLipofuscinRetinal PigmentsRetinoidsA2E (N-retinylidene-N-retinylethanolamine)lipofuscin fluorescenceliquid chromatography/mass spectrometry (LC/MS), melaninretinaRPE lipofuscin

Identifiers

PMID32244898
PMCPMC7144568
OpenAlexW3010881680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.