Evidence map›Paper›PMID 32244854›Full record

ArticleInternational journal of molecular sciences2020

Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage.

Andrés D Klein, Javier González de la Vega, Silvana Zanlungo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Hepatocellular carcinoma as a complication of Niemann-Pick disease type C1.American journal of medical genetics. Part A · 2021
    Article
  9. Review
  10. Understanding and Treating Niemann-Pick Type C Disease: Models Matter.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Andrés D KleinCentro de Genética y Genómica, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7590943, Chile.ORCID 0000-0002-9951-2174
Javier González de la VegaDepartamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Silvana ZanlungoDepartamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Pontificia Universidad Católica de Chile · CLUniversidad del Desarrollo · CL

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1180337, 1190334Horizon 2020 Framework Programme 734825
6 · The paper itself

Abstract

Niemann-Pick type C (NPC), a lysosomal storage disorder, is mainly caused by mutations in the

Indexed as

AgingAnimalsComplement C3Foam CellsLiverMice, Inbred C57BLNiemann-Pick Disease, Type CComplement C3cholesterolcomplement cascadefoam cellsliver damagelysosomal storage diseasesNiemann–Pick type C disease

Identifiers

PMID32244854
PMCPMC7139721
OpenAlexW3010674614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.