Evidence map›Paper›PMID 32244845›Full record

ArticleGenes2020

Altered Expression of GABAergic Markers in the Forebrain of Young and Adult

Giovanni Provenzano, Angela Gilardoni, Marika Maggia, Mattia Pernigo, Paola Sgadò, Simona Casarosa, Yuri Bozzi

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Intricacies of GABAInternational journal of molecular sciences · 2021
    Review
  9. GABAergic System Dysfunction in Autism Spectrum Disorders.Frontiers in cell and developmental biology · 2021
    Review
  10. The Parvalbumin Hypothesis of Autism Spectrum Disorder.Frontiers in cellular neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giovanni ProvenzanoDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38068 Rovereto, Italy.
Angela GilardoniDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38068 Rovereto, Italy.
Marika MaggiaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38068 Rovereto, Italy.
Mattia PernigoDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38068 Rovereto, Italy.
Paola SgadòCenter for Mind/Brain Sciences (CIMeC), University of Trento, 38068 Rovereto, Italy.
Simona CasarosaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38068 Rovereto, Italy.
Yuri BozziCenter for Mind/Brain Sciences (CIMeC), University of Trento, 38068 Rovereto, Italy.
University of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired function of GABAergic interneurons, and the subsequent alteration of excitation/inhibition balance, is thought to contribute to autism spectrum disorders (ASD). Altered numbers of GABAergic interneurons and reduced expression of GABA receptors has been detected in the brain of ASD subjects and mouse models of ASD. We previously showed a reduced expression of GABAergic interneuron markers parvalbumin (PV) and somatostatin (SST) in the forebrain of adult mice lacking the

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsAutism Spectrum DisorderDisease Models, AnimalEngrailed 2 ProteinFemaleGABAergic NeuronsHippocampusHomeodomain ProteinsInterneuronsMaleMiceMice, KnockoutNerve Tissue ProteinsParvalbuminsReceptors, GABAEngrailed 2 ProteinHomeodomain ProteinsNerve Tissue ProteinsParvalbuminsReceptors, GABASomatostatinautismdevelopmentGABAhippocampusinterneuronmouseparvalbuminreceptorsomatosensorysomatostatin

Identifiers

PMID32244845
PMCPMC7231099
OpenAlexW3014805823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.