Evidence map›Paper›PMID 32244736›Full record

ArticlePharmaceutics2020

PLGA Microspheres with Alginate-Coated Large Pores for the Formulation of an Injectable Depot of Donepezil Hydrochloride.

Dohyun Kim, Tae Hee Han, Seong-Chul Hong, Sun Jae Park, Yong Hak Lee, Hyeongmin Kim, Minwoo Park, Jaehwi Lee

Abstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dohyun KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Tae Hee HanCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Seong-Chul HongCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Sun Jae ParkCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Yong Hak LeeCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Hyeongmin KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Minwoo ParkCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Jaehwi LeeCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.ORCID 0000-0003-3696-2626

Funding

National Research Foundation of Korea 2015R1A5A1008958National Research Foundation of Korea 2018R1D1A1A09083443
6 · The paper itself

Abstract

As the main symptom of Alzheimer's disease-related dementia is memory loss, patient compliance for donepezil hydrochloride (donepezil), administered as once-daily oral formulations, is poor. Thus, we aimed to design poly(lactic-

Indexed as

burst releaseconvolutiondonepezil depotdrug loadingpore closingpore sizeporosityporous microspheresustained release

Identifiers

PMID32244736
PMCPMC7238133

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.