Evidence map›Paper›PMID 32244620›Full record

ArticleSensors (Basel, Switzerland)2020

Head-Mounted Display-Based Microscopic Imaging System with Customizable Field Size and Viewpoint.

Tadayoshi Aoyama, Sarau Takeno, Masaru Takeuchi, Yasuhisa Hasegawa

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tadayoshi AoyamaDepartment of Micro-Nano Mechanical Science and Engineering, Nagoya University, Furo-cho 1, Chikusa Word, Nagoya 464-8603, Japan.ORCID 0000-0001-7860-0725
Sarau TakenoDepartment of Micro-Nano Mechanical Science and Engineering, Nagoya University, Furo-cho 1, Chikusa Word, Nagoya 464-8603, Japan.
Masaru TakeuchiDepartment of Micro-Nano Mechanical Science and Engineering, Nagoya University, Furo-cho 1, Chikusa Word, Nagoya 464-8603, Japan.ORCID 0000-0001-9304-4667
Yasuhisa HasegawaDepartment of Micro-Nano Mechanical Science and Engineering, Nagoya University, Furo-cho 1, Chikusa Word, Nagoya 464-8603, Japan.

Funding

Japan Science and Technology Agency JPMJPR18J1
6 · The paper itself

Abstract

In recent years, the use of microinjections has increased in life science and biotechnology fields; specific examples include artificial insemination and gene manipulation. Microinjections are mainly performed based on visual information; thus, the operator needs high-level skill because of the narrowness of the visual field. Additionally, microinjections are performed as the operator views a microscopic image on a display; the position of the display requires the operator to maintain an awkward posture throughout the procedure. In this study, we developed a microscopic image display apparatus for microinjections based on a view-expansive microscope. The prototype of the view-expansive microscope has problems related to the variations in brightness and focal blur that accompany changes in the optical path length and amount of reflected light. Therefore, we propose the use of a variable-focus device to expand the visual field and thus circumvent the above-mentioned problems. We evaluated the observable area of the system using this variable-focus device. We confirmed that the observable area is 261.4 and 13.9 times larger than that of a normal microscope and conventional view-expansive microscopic system, respectively. Finally, observations of mouse embryos were carried out by using the developed system. We confirmed that the microscopic images can be displayed on a head-mounted display in real time with the desired point and field sizes.

Indexed as

User-Computer InterfaceAnimalsEmbryo, MammalianEquipment DesignHumansMiceMicroinjectionsMicroscopyHMDmicro-macro interfaceview-expansive microscope

Identifiers

PMID32244620
PMCPMC7181164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.