Evidence map›Paper›PMID 32244618›Full record

ArticleSports (Basel, Switzerland)2020

Ultramarathon Plasma Metabolomics: Phosphatidylcholine Levels Associated with Running Performance.

Tracy B Høeg, Kenneth Chmiel, Alexandra E Warrick, Sandra L Taylor, Robert H Weiss

Open access · goldAbstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Metabolomics in Exercise and Sports: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tracy B HøegDepartment of Physical Medicine & Rehabilitation, University of California, Sacramento, CA 95817, USA.ORCID 0000-0002-2341-6573
Kenneth ChmielDivision of Nephrology, Department of Medicine, University of California, Davis, CA 95817, USA.
Alexandra E WarrickDepartment of Physical Medicine & Rehabilitation, University of California, Sacramento, CA 95817, USA.
Sandra L TaylorDivision of Biostatistics, Department of Public Health Sciences, University of California, Davis, CA 95616, USA.
Robert H WeissDivision of Nephrology, Department of Medicine, University of California, Davis, CA 95817, USA.
California State University, Sacramento · USUniversity of California, Davis · USVA Northern California Health Care System · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Napa Medical Research Foundation NANCATS NIH HHS UL1 TR001860Western States Endurance Run Foundation NA
6 · The paper itself

Abstract

The purpose of this study was to identify plasma metabolites associated with superior endurance running performance. In 2016, participants at the Western States Endurance Run (WSER), a 100-mile (161-km) foot race, underwent non-targeted metabolomic testing of their post-race plasma. Metabolites associated with faster finish times were identified. Based on these results, runners at the 2017 WSER underwent targeted metabolomics testing, including lipidomics and choline levels. The 2017 participants' plasma metabolites were correlated with finish times and compared with non-athletic controls. In 2016, 427 known molecules were detected using non-targeted metabolomics. Four compounds, all phosphatidylcholines (PCs) were associated with finish time (False Discovery Rate (FDR) < 0.05). All were higher in faster finishers. In 2017, using targeted PC analysis, multiple PCs, measured pre- and post-race, were higher in faster finishers (FDR < 0.05). The majority of PCs was noted to be higher in runners (both pre- and post-race) than in controls (FDR < 0.05). Runners had higher choline levels pre-race compared to controls (

Indexed as

enduranceexerciseperformancephysiologyrunningultramarathon

Identifiers

PMID32244618
PMCPMC7240692
OpenAlexW3014474950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.