Evidence map›Paper›PMID 32244595›Full record

ArticleJournal of functional biomaterials2020

Properties and Skin Compatibility of Films Based on Poly(Lactic Acid) (PLA) Bionanocomposites Incorporating Chitin Nanofibrils (CN).

Maria-Beatrice Coltelli, Laura Aliotta, Alessandro Vannozzi, Pierfrancesco Morganti, Luca Panariello, Serena Danti, Simona Neri, Cristina Fernandez-Avila, Alessandra Fusco, Giovanna Donnarumma and 1 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. 3D Printed Piezoelectric BaTiOBioengineering (Basel, Switzerland) · 2024
    Article
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  3. Review
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  19. Article
  20. Modification of PLA-Based Films by Grafting or Coating.Journal of functional biomaterials · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria-Beatrice ColtelliDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Laura AliottaDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Alessandro VannozziDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Pierfrancesco MorgantiAcademy of History of Health Care Art, 00193 Rome, Italy.
Luca PanarielloDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Serena DantiDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Simona NeriIRIS Technology Solutions S.L, 08860 Castelldefels, Barcelona, Spain.
Cristina Fernandez-AvilaIRIS Technology Solutions S.L, 08860 Castelldefels, Barcelona, Spain.
Alessandra FuscoDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Giovanna DonnarummaDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.
Andrea LazzeriDepartment of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy.

Funding

Bio Based Industries Joint Undertaking (BBI JU) 745839Horizon 2020 Framework Programme 745839
6 · The paper itself

Abstract

Nanobiocomposites suitable for preparing skin compatible films by flat die extrusion were prepared by using plasticized poly(lactic acid) (PLA), poly(butylene succinate-co-adipate) (PBSA), and Chitin nanofibrils as functional filler. Chitin nanofibrils (CNs) were dispersed in the blends thanks to the preparation of pre-nanocomposites containing poly(ethylene glycol). Thanks to the use of a melt strength enhancer (Plastistrength) and calcium carbonate, the processability and thermal properties of bionanocomposites films containing CNs could be tuned in a wide range. Moreover, the resultant films were flexible and highly resistant. The addition of CNs in the presence of starch proved not advantageous because of an extensive chain scission resulting in low values of melt viscosity. The films containing CNs or CNs and calcium carbonate resulted biocompatible and enabled the production of cells defensins, acting as indirect anti-microbial. Nevertheless, tests made with

Indexed as

anti-microbialchitin nanofibrilspoly(butylene succinate)poly(lactic acid)skin compatibilitystarch

Identifiers

PMID32244595
PMCPMC7353621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.