Evidence map›Paper›PMID 32244505›Full record

ArticleInternational journal of molecular sciences2020

Amination of Graphene Oxide Leads to Increased Cytotoxicity in Hepatocellular Carcinoma Cells.

Milena Georgieva, Bela Vasileva, Giorgio Speranza, Dayong Wang, Kalin Stoyanov, Milena Draganova-Filipova, Plamen Zagorchev, Victoria Sarafian, George Miloshev, Natalia Krasteva

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  8. Review
  9. Genotoxicity of Graphene-Based Materials.Nanomaterials (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Milena GeorgievaInstitute of Molecular Biology "Roumen Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Bela VasilevaInstitute of Molecular Biology "Roumen Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Giorgio SperanzaFunctional Materials and Photonic Structure, Center for Materials and Microsystems, Fondazione Bruno Kessler, I-38123 Povo, Italy.
Dayong WangDepartment of Biochemistry and Molecular Biology, Medical School in Southeast University, Nanjing 210009, China.
Kalin StoyanovDepartment of Automation, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.
Milena Draganova-FilipovaDepartment of Medical Biology, Medical Faculty, Medical University - Plovdiv, 4000 Plovdiv, Bulgaria.
Plamen ZagorchevDepartment of Physics and Biophysics, Faculty of Pharmacy, Medical University - Plovdiv, 4000 Plovdiv, Bulgaria.
Victoria SarafianDepartment of Medical Biology, Medical Faculty, Medical University - Plovdiv, 4000 Plovdiv, Bulgaria.
George MiloshevInstitute of Molecular Biology "Roumen Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Natalia KrastevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Bulgarian Academy of Sciences · BGMedical University Plovdiv · BGFondazione Bruno Kessler · ITSoutheast University · CNUniversity of Chemical Technology and Metallurgy · BG

Funding

Bulgarian National Research Fund KP06-N31/15 and DN11/15National Research Foundation DNTS/ 01/6/2016NATO Science for Peace and Security programme NATO SPS MYP G5266
6 · The paper itself

Abstract

Clinically, there is an urgent need to identify new therapeutic strategies for selectively treating cancer cells. One of the directions in this research is the development of biocompatible therapeutics that selectively target cancer cells. Here, we show that novel aminated graphene oxide (haGO-NH

Indexed as

AminationApoptosisCarcinoma, HepatocellularCell Line, TumorCell MembraneCell SurvivalGraphiteHepatocytesHep G2 CellsHumansLiver NeoplasmsMitochondriaNanoparticlesReactive Oxygen Speciesgraphene oxideGraphiteReactive Oxygen SpeciescytotoxicitygenotoxicityGOhaGO-NH2HepG2hydroxylaminenanoparticle functionalization

Identifiers

PMID32244505
PMCPMC7177364
OpenAlexW3014832780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.