Evidence map›Paper›PMID 32244499›Full record

ArticleInternational journal of molecular sciences2020

Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis.

Qing Jiang, Xin Qin, Carolina Andrea Yoshida, Hisato Komori, Kei Yamana, Shinsuke Ohba, Hironori Hojo, Brad St Croix, Viviane K S Kawata-Matsuura, Toshihisa Komori

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Vascular Calcification in CKD: More Complex Than Ever.Journal of the American Society of Nephrology : JASN · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1.World journal of gastrointestinal oncology · 2021
    Review
  8. Article
  9. Molecular Mechanisms of Chondrocyte Proliferation and Differentiation.Frontiers in cell and developmental biology · 2021
    Review
  10. Molecular Processes in Chondrocyte Biology.International journal of molecular sciences · 2020
    Article
  11. Expression of a Constitutively Active Form ofInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Qing JiangBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Xin QinBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Carolina Andrea YoshidaBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Hisato KomoriBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.ORCID 0000-0001-6802-949X
Kei YamanaTeijin Institute for Bio-Medical Research, Teijin Limited, Tokyo 100-8585, Japan.
Shinsuke OhbaDepartment of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Hironori HojoDepartment of Bioengineering, the University of Tokyo Graduate School of Engineering, Tokyo 113-0033, Japan.
Brad St CroixTumor Angiogenesis Unit, National Cancer Institute (NCI), National Institutes of Health (NIH), Frederick, MD 21702, USA.
Viviane K S Kawata-MatsuuraBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Toshihisa KomoriBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Nagasaki University · JPNational Institutes of Health · USTeijin (Japan) · JPThe University of Tokyo · JP

Funding

Functional Analysis of TEM5 and TEM8ZIABC010484 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ST CROIX, BRADLEY D · 2009 to 2025
$9.3M
Japanese Ministry of Education, Culture, Sports, Science and Technology 19K24124; 19K18946; 18K17017; 18H05283
6 · The paper itself

Abstract

Antxr1/Tem8 is highly expressed in tumor endothelial cells and is a receptor for anthrax toxin. Mutation of

Indexed as

AnimalsApoptosisCartilageCell DifferentiationCell ProliferationChondrocytesCore Binding Factor Alpha 1 SubunitEndothelial CellsFemaleFemurMaleMiceMice, Inbred C57BLMice, KnockoutMicrofilament ProteinsMutationAntxr1 protein, mouseCore Binding Factor Alpha 1 SubunitMicrofilament ProteinsReceptors, Cell SurfaceRunx2 protein, mouseAntxr1apoptosischondrocyte proliferationGAPO syndromeRunx2

Identifiers

PMID32244499
PMCPMC7178079
OpenAlexW3014892847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.