Evidence map›Paper›PMID 32244431›Full record

ArticleInternational journal of molecular sciences2020

Inhibitory Effective Perturbations of Cilobradine (DK-AH269), A Blocker of HCN Channels, on the Amplitude and Gating of Both Hyperpolarization-Activated Cation and Delayed-Rectifier Potassium Currents.

Te-Ling Lu, Te-Jung Lu, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Zingerone Modulates Neuronal Voltage-Gated NaInternational journal of molecular sciences · 2022
    Article
  4. Article
  5. Bidirectional flow of the funny current (IProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Characterization of the Synergistic Inhibition ofInternational journal of molecular sciences · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Te-Ling LuSchool of Pharmacy, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0003-1408-6004
Te-Jung LuDepartment of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan 71703, Taiwan.
Sheng-Nan WuInstitute of Basic Medical Sciences, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
Chung Hwa University of Medical Technology · TWChina Medical University · TW

Funding

China Medical University CMU101-ASIA-07Ministry of Science and Technology MOST-108-2314-B-006-094National Cheng Kung University NCKUH-10709001
6 · The paper itself

Abstract

Cilobradine (CIL, DK-AH269), an inhibitor of hyperpolarization-activated cation current (

Indexed as

AnimalsBenzazepinesCationsCell Line, TumorHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIon TransportIvabradineKineticsPatch-Clamp TechniquesPiperidinesPituitary NeoplasmsPotassiumShab Potassium ChannelsSodiumBenzazepinesCationscilobradineHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIvabradinePiperidinesPotassiumShab Potassium ChannelsSodiumzatebradinecilobradinecurrent kineticsdelayed-rectifier K+ currentheart cellhyperpolarization-activated cation currentimpedance magnitude analysispituitary cell

Identifiers

PMID32244431
PMCPMC7177279
OpenAlexW3014263332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.