Evidence map›Paper›PMID 32244296›Full record

ArticleBiomolecules2020

Effect of Substrate Reduction Therapy in Comparison to Enzyme Replacement Therapy on Immune Aspects and Bone Involvement in Gaucher Disease.

Renuka P Limgala, Ozlem Goker-Alpan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Zebra-Sphinx: Modeling Sphingolipidoses in Zebrafish.International journal of molecular sciences · 2023
    Review
  7. Gaucher disease - more than just a rare lipid storage disease.Journal of molecular medicine (Berlin, Germany) · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Renuka P LimgalaLysosomal and Rare Disorders Research and Treatment Center (LDRTC), Fairfax, VA 22030, USA.ORCID 0000-0001-6957-6284
Ozlem Goker-AlpanLysosomal and Rare Disorders Research and Treatment Center (LDRTC), Fairfax, VA 22030, USA.
Lysosomal and Rare Disorders Research and Treatment Center · US

Funding

Sanofi Genzyme GZ-2014-11295
6 · The paper itself

Abstract

Gaucher disease (GD) is caused by mutations in the

Indexed as

Enzyme Replacement TherapyAdolescentAdultBone and BonesChildFemaleGaucher DiseaseHumansMaleMiddle AgedYoung Adultbone involvementenzyme replacement therapyGaucher diseaseMIP-1βOsteoimmunologyOsteopontinRANK/RANKLsubstrate reduction therapy

Identifiers

PMID32244296
PMCPMC7226435
OpenAlexW3014919052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.