Evidence map›Paper›PMID 32244286›Full record

ArticleCells2020

Characterization of Sialic Acid-Binding Immunoglobulin-Type Lectins in Fish Reveals Teleost-Specific Structures and Expression Patterns.

Kim F Bornhöfft, Joan Martorell Ribera, Torsten Viergutz, Marzia T Venuto, Ulrike Gimsa, Sebastian P Galuska, Alexander Rebl

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kim F BornhöfftInstitute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Joan Martorell RiberaInstitute of Genome Biology, FBN, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.ORCID 0000-0002-8665-4624
Torsten ViergutzInstitute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Marzia T VenutoInstitute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.ORCID 0000-0002-8995-1536
Ulrike GimsaInstitute of Behavioural Physiology, FBN, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.ORCID 0000-0003-2248-5793
Sebastian P GaluskaInstitute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Alexander ReblInstitute of Genome Biology, FBN, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.ORCID 0000-0002-2918-7433
Research Institute for Farm Animal Biology (FBN) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular glycocalyx of vertebrates is frequently decorated with sialic acid residues. These sialylated structures are recognized by sialic acid-binding immunoglobulin-type lectins (Siglecs) of immune cells, which modulate their responsiveness. Fifteen Siglecs are known to be expressed in humans, but only four Siglecs are regularly present in fish: Siglec1, CD22, myelin-associated glycoprotein (MAG), and Siglec15. While several studies have dealt with the physiological roles of these four Siglecs in mammals, little is known about Siglecs in fish. In the present manuscript, the expression landscapes of these Siglecs were determined in the two salmonid species

Indexed as

Gene Expression RegulationAmino Acid SequenceAnimalsFishesGene DosageGene Expression ProfilingHumansMiceModels, MolecularOrgan SpecificitySequence Homology, Amino AcidSialic Acid Binding Immunoglobulin-like LectinsSpecies SpecificityStress, PsychologicalSialic Acid Binding Immunoglobulin-like Lectinsacute stressITIMSalmonidaesialic acidssiglecsvertebrate evolution

Identifiers

PMID32244286
PMCPMC7226832
OpenAlexW3014131530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.