Evidence map›Paper›PMID 32244059›Full record

ReviewHeart rhythm2020

SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes.

Cheng-I Wu, Pieter G Postema, Elena Arbelo, Elijah R Behr, Connie R Bezzina, Carlo Napolitano, Tomas Robyns, Vincent Probst, Eric Schulze-Bahr, Carol Ann Remme and 1 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Heart rhythm, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04373759 (Cardiac Arrest Incidence and Outcome Among Patient With COVID-19 Pneumonia in French ICUs), which is not on this map. Cited by 119 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 5 pooled it
30.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04373759 completednot on this map

Cardiac Arrest Incidence and Outcome Among Patient With COVID-19 Pneumonia in French ICUs

Typeobservational_patient_registrySponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2020 to 2020Enrolled186ConditionsSars-CoV2, Covid-19ArmsCardiopulmonary resuscitation, Modified Rankin score
3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 5 syntheses or guidelines pooled it, 222 citations in OpenAlex.

  1. Pooled it
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  15. The Potential Mechanisms of Arrhythmia in Coronavirus disease-2019.International journal of medical sciences · 2024
    Review
  16. Article
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  20. Screening, diagnosis and follow-up of Brugada syndrome in children: a Dutch expert consensus statement.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Review

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 8 countries.

Cheng-I WuDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address: c.wu@amsterdamumc.nl.
Pieter G PostemaDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart).
Elena ArbeloArrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Institut d'Investigació August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Elijah R BehrEuropean Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); Cardiology Clinical Academic Group, St George's University of London and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Connie R BezzinaDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart).
Carlo NapolitanoEuropean Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); Molecular Cardiology and Medicine Division, Istituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Tomas RobynsEuropean Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
Vincent ProbstEuropean Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); l'Institut du thorax, Service de Cardiologie du CHU de Nantes, Hopital Nord, Nantes Cedex, France.
Eric Schulze-BahrEuropean Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart); Institute for Genetics of Heart Diseases (IfGH), Division of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.
Carol Ann RemmeDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart).
Arthur A M WildeDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart). Electronic address: a.a.wilde@amsterdamumc.nl.
Amsterdam Neuroscience · NLCentre Hospitalier Universitaire de Nantes · FRCentro de Investigación en Red en Enfermedades Cardiovasculares · ESERN GUARD-Heart · NLIstituti Clinici Scientifici Maugeri · ITSt George's, University of London · GBTaipei Veterans General Hospital · TWUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ever since the first case was reported at the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease 2019 (COVID-19) has become a serious threat to public health globally in short time. At this point in time, there is no proven effective therapy. The interactions with concomitant disease are largely unknown, and that may be particularly pertinent to inherited arrhythmia syndrome. An arrhythmogenic effect of COVID-19 can be expected, potentially contributing to disease outcome. This may be of importance for patients with an increased risk of cardiac arrhythmias, either secondary to acquired conditions or comorbidities or consequent to inherited syndromes. Management of patients with inherited arrhythmia syndromes such as long QT syndrome, Brugada syndrome, short QT syndrome, and catecholaminergic polymorphic ventricular tachycardia in the setting of the COVID-19 pandemic may prove particularly challenging. Depending on the inherited defect involved, these patients may be susceptible to proarrhythmic effects of COVID-19-related issues such as fever, stress, electrolyte disturbances, and use of antiviral drugs. Here, we describe the potential COVID-19-associated risks and therapeutic considerations for patients with distinct inherited arrhythmia syndromes and provide recommendations, pending local possibilities, for their monitoring and management during this pandemic.

Indexed as

BetacoronavirusArrhythmias, CardiacCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2SyndromeBrugada syndromeCatecholaminergic polymorphic ventricular tachycardiaCOVID-19Long QT syndromeSARS-CoV-2Short QT syndrome

Identifiers

PMID32244059
PMCPMC7156157
OpenAlexW3014374025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.