Evidence map›Paper›PMID 32243952›Full record

ArticleThe Journal of hospital infection2020

Antimicrobial resistance in southern China: results of prospective surveillance in Dongguan city, 2017.

J Wang, M Zhou, G Huang, Z Guo, J Sauser, A Metsini, D Pittet, W Zingg

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

J WangInfection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland; Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland; Department of Infection Control, Dongguan Hospital of Traditional Chinese Medicine, Dongguan city, Guang Dong Province, China.
M ZhouDepartment of Infection Control, Dongguan Tung Wah Hospital, Sun Yat-sen University, Dongguan city, Guang Dong Province, China; Dongguan Nosocomial Infection Control and Quality Improvement Centre, Dongguan city, Guang Dong Province, China.
G HuangDepartment of Infection Control, Dongguan Tung Wah Hospital, Sun Yat-sen University, Dongguan city, Guang Dong Province, China; Dongguan Nosocomial Infection Control and Quality Improvement Centre, Dongguan city, Guang Dong Province, China.
Z GuoDepartment of Microbiology, Dongguan Tung Wah Hospital, Sun Yat-sen University, Dongguan city, Guang Dong Province, China.
J SauserInfection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
A MetsiniInfection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
D PittetInfection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
W ZinggInfection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College of London, London, UK. Electronic address: Walter.Zingg@hcuge.ch.
University of Geneva · CHSun Yat-sen University · CNDongguan People’s Hospital · CNTung Wah Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have estimated the burden of infections due to antimicrobial-resistant (AMR) pathogens in China.

aimTo summarize antimicrobial resistance and assess the frequency of community-associated infections (CAIs) and healthcare-associated infections (HCAIs) due to AMR pathogens in Dongguan city, China.

methodsSeven acute care hospitals provided antimicrobial susceptibility data for 2017, from which 'bug-drug' combinations were analysed. To calculate incidence proportions of CAI and incidence densities of HCAI, data from three tertiary care hospitals were merged with patient data, obtained from the Dongguan Nosocomial Infection Surveillance System.

findingsA total of 16,548 pathogens were analysed. Non-susceptibility to third-generation cephalosporins (3GCs) in Escherichia coli and Klebsiella pneumoniae was 43.9% and 30.2%, respectively. Non-susceptibility to carbapenems in Pseudomonas aeruginosa and Acinetobacter baumannii was 29.5% and 50.9%, respectively. A quarter of Staphylococcus aureus (26.3%) were non-susceptible to oxacillin. The incidence density of HCAI due to E. coli non-susceptible to 3GCs and fluoroquinolones combined was 0.09 (95% confidence interval: 0.07-0.11) per 1000 patient-days. Both E. coli and K. pneumoniae were the predominant pathogens isolated from blood. Compared with the 2017 European Antimicrobial Resistance Surveillance Network report, the incidence proportion of bloodstream infections due to multidrug-resistant E. coli was significantly higher (14.9% and 4.6%, respectively).

conclusionThe incidence of non-susceptible bug-drug combinations in Dongguan city was lower compared with China as a whole. Non-susceptible bug-drug combinations were significantly more frequent in HCAI compared with CAI. The incidence proportion of bloodstream infections due to multidrug-resistant pathogens in Dongguan City was higher compared with Europe.

Indexed as

Drug Resistance, Multiple, BacterialEpidemiological MonitoringAnti-Bacterial AgentsBacteriaChinaCommunity-Acquired InfectionsCost of IllnessCross InfectionHumansMicrobial Sensitivity TestsProspective StudiesAnti-Bacterial AgentsAntimicrobial resistanceChinaDongguanIncidence densityIncidence proportionMultidrug-resistant pathogensSurveillance

Identifiers

PMID32243952
PMCPMC7270154
OpenAlexW3014747633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.