Evidence map›Paper›PMID 32243733›Full record

ArticleBJS open2020

Effect of high ligation on survival of patients undergoing surgery for primary colorectal cancer and synchronous liver metastases.

S Matsui, K Okabayashi, H Hasegawa, M Tsuruta, K Shigeta, T Ishida, T Yamada, T Kondo, S Yamauchi, K Sugihara and 1 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BJS open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

S MatsuiDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-7509-9365
K OkabayashiDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
H HasegawaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
M TsurutaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
K ShigetaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-1596-4200
T IshidaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
T YamadaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
T KondoDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
S YamauchiDepartment of Surgical Oncology, Tokyo Medical and Dental University, Tokyo, Japan.
K SugiharaDepartment of Surgical Oncology, Tokyo Medical and Dental University, Tokyo, Japan.
Y KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Keio University · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough R0 surgery is recommended for stage IV colorectal cancer, the degree of required lymphadenectomy has not been established. The aim of this study was to investigate the prognostic impact of high ligation (HL) of the feeding artery and the number of retrieved lymph nodes after R0 surgery for colorectal cancer and synchronous colorectal cancer liver metastasis (CRLM).

methodsThis was a multi-institutional retrospective analysis of patients with colorectal cancer and synchronous CRLM who had R0 surgery between January 1997 and December 2007. Clinical and pathological features were compared in patients who underwent HL and those who had a low ligation (LL). Kaplan-Meier analysis was performed to estimate the effect of HL on overall survival (OS). The impact of several risk factors on survival was analysed using the Cox proportional hazards model.

resultsOf 549 patients, 409 (74·5 per cent) had HL. Median follow-up was 51·4 months. HL significantly improved the 5-year OS rate (58·2 per cent versus 49·3 per cent for LL; P = 0·017). Multivariable analysis revealed HL to be a significant prognostic factor compared with LL (5-year mortality: hazard ratio (HR) 0·68, 95 per cent c.i. 0·51 to 0·90; P = 0·007). In subgroup analysis, the positive effect of HL on OS was greatest in patients with lymph node metastasis.

conclusionHL of the feeding artery was associated with improved OS in patients with colorectal cancer and synchronous CRLM after R0 surgery.

Indexed as

AgedColorectal NeoplasmsFemaleHepatectomyHumansJapanLigationLiver NeoplasmsLymph NodesMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSurvival Analysis

Identifiers

PMID32243733
PMCPMC7260402
OpenAlexW3014565519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.