Evidence map›Paper›PMID 32243416›Full record

ArticleCornea2020

Anterior Segment Optical Coherence Tomography in Ocular Argyrosis.

Xu He, Nathaniel L Simmons, Rachel A F Wozniak

Open access · greenAbstract readCase Reports
In one paragraph

Article in Cornea, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Ocular argyrosis.Eye (London, England) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xu HeDepartment of Ophthalmology, University of Rochester Medical Center, Rochester, NY.
Nathaniel L Simmons
Rachel A F Wozniak
University of Rochester Medical Center · USResearch to Prevent Blindness · US

Funding

Development of Novel Ophthalmic AntibioticsK08EY029012 · NEI · UNIVERSITY OF ROCHESTER · PI WOZNIAK, RACHEL A F · 2018 to 2022
$963k
NEI NIH HHS K08 EY029012
6 · The paper itself

Abstract

purposeTo highlight the novel application of anterior segment optical coherence tomography (AS-OCT) to detect corneal silver deposition in a case of ocular argyrosis.

methodsThis is a case report and review of the literature.

resultsA 67-year-old man with a 30-year history of chronic occupational exposure to silver-halides secondary to photographic film manufacturing presented with significant ocular argyrosis. His ophthalmic examination was notable for bilateral, widespread pinpoint gray deposits throughout his conjunctiva and cornea at the level of Descemet membrane. Further evaluation with AS-OCT showed deposition in 2 distinct, diffusely hyperreflective bands, corresponding to Bowman layer and Descemet membrane.

conclusionsAS-OCT provides a useful imaging modality in evaluating corneal deposition diseases. In this case of ocular argyrosis, AS-OCT led to the detection of a hyperreflective Bowman layer and Descemet membrane, representing silver deposition in both these anatomic locations.

Indexed as

AgedArgyriaCorneaEye DiseasesHumansMaleMicroscopy, ConfocalTomography, Optical Coherence

Identifiers

PMID32243416
PMCPMC7529654
OpenAlexW3014846783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.