Evidence map›Paper›PMID 32243266›Full record

ArticleASAIO journal (American Society for Artificial Internal Organs : 1992)2020

Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 in Shanghai, China.

Xin Li, Zhen Guo, Bailing Li, Xiaolin Zhang, Rui Tian, Wei Wu, Zhongwei Zhang, Yunfei Lu, Nan Chen, Sean P Clifford and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ASAIO journal (American Society for Artificial Internal Organs : 1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 4 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 171 citations in OpenAlex.

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  16. The role of extracorporeal membrane oxygenation in COVID-19.Journal of cardiothoracic and vascular anesthesia · 2022
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Xin LiFrom the Department of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhen GuoDepartment of Extracorporeal Circulation, Shanghai Chest Hospital, Shanghai, China.
Bailing LiDepartment of Cardiovascular Surgery, Changhai Hospital of Shanghai, Shanghai, China.
Xiaolin ZhangDepartment of Intensive Care Unit, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Rui TianDepartment of Emergency and Critical Care, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wei WuDepartment of Intensive Care Unit, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhongwei ZhangDepartment of Critical Care, Shanghai Zhongshan Hospital, Fudan University, Shanghai, China.
Yunfei LuDepartment of Traditional Chinese Medicine, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Nan ChenDepartment of CRRT Center, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Sean P CliffordDepartment of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, Kentucky.
Jiapeng HuangDepartment of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, Kentucky.
Shanghai Public Health Clinical Center · CNZhongshan Hospital · CNFudan University Shanghai Cancer Center · CNSecond Military Medical University · CNShanghai Chest Hospital · CNShanghai Jiao Tong University · CNUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe cases of coronavirus disease 2019 (COVID-19) cannot be adequately managed with mechanical ventilation alone. The role and outcome of extracorporeal membrane oxygenation (ECMO) in the management of COVID-19 is currently unclear. Eight COVID-19 patients have received ECMO support in Shanghai with seven with venovenous (VV) ECMO support and one veno arterial (VA) ECMO during cardiopulmonary resuscitation. As of March 25, 2020, four patients died (50% mortality), three patients (37.5%) were successfully weaned off ECMO after 22, 40, and 47 days support, respectively, but remain on mechanical ventilation. One patient is still on VV ECMO with mechanical ventilation. The partial pressure of oxygen/fractional of inspired oxygen ratio before ECMO initiation was between 54 and 76, and all were well below 100. The duration of mechanical ventilation before ECMO ranged from 4 to 21 days. Except the one emergent VA ECMO during cardiopulmonary resuscitation, other patients were on ECMO support for between 18 and 47 days. In conclusion, ensuring effective, timely, and safe ECMO support in COVID-19 is key to improving clinical outcomes. Extracorporeal membrane oxygenation support might be an integral part of the critical care provided for COVID-19 patients in centers with advanced ECMO expertise.

Indexed as

BetacoronavirusExtracorporeal Membrane OxygenationAdultAgedAged, 80 and overChinaCoronavirus InfectionsCOVID-19FemaleHumansMaleMiddle AgedPandemicsPneumonia, ViralRespiration, ArtificialRetrospective Studies

Identifiers

PMID32243266
PMCPMC7273861
OpenAlexW3012955332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.