Evidence map›Paper›PMID 32242947›Full record

SynthesisJournal of medical virology2020

Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2: A systematic review and meta-analysis.

Yinghao Cao, Xiaoling Liu, Lijuan Xiong, Kailin Cai

2 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 179 papers, 23 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 23 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04661631 unknown statusnot on this map

Lung Ultrasound in COVID-19 Infection Screening for Patients With Indication of Emergency Surgery

Typeobservational_patient_registrySponsorFundacion Clinica Valle del LiliRan2020 to 2021Enrolled451ConditionsUltrasonography, Lung Diseases, Surgical Procedure, Covid19ArmsLung ultrasound
NCT05167357 nacompletednot on this mapstarted 2021, after this paper: background citation

Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19

TypeinterventionalSponsorInstitut de Formation et de Recherche en Médecine de MontagneRan2021 to 2021Enrolled68ConditionsCovid19, SARS-CoV2 Infection, Hypoxia, AltitudeArmsCOVID19
3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 23 syntheses or guidelines pooled it, 357 citations in OpenAlex.

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  7. A Review of Prolonged Post-COVID-19 Symptoms and Their Implications on Dental Management.International journal of environmental research and public health · 2021
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  9. COVID-19 in People Living with HIV: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
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  18. COVID-19 and pregnancy: A review of clinical characteristics, obstetric outcomes and vertical transmission.The Australian & New Zealand journal of obstetrics & gynaecology · 2020
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  20. Guideline

119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yinghao CaoDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xiaoling LiuDepartment of Endocrinology, Liyuan Hospital, Tongji Medical College, Huazhong University of Since and Technology, Wuhan, Hubei, China.
Lijuan XiongDepartment of Nosocomial Infection Management, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Kailin CaiDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.ORCID 0000-0002-2572-0907
Union Hospital · CNHuazhong University of Science and Technology · CN

Funding

Biotechnology and Biological Sciences Research Council BB/N013468/1Free Innovation Pre-research Fund and Platform Scientific Research Fund in 2019 02.03.2019-111Science and Technology Department of Hubei Province 2018CFC884
6 · The paper itself

Abstract

backgroundCurrently, the epidemic of coronavirus disease 2019 (COVID-19) has begun to spread worldwide. We aim to explore reliable evidence for the diagnosis and treatment of the COVID-19 by analyzing all the published studies by Chinese scholars on the clinical and imaging features in novel coronavirus pneumonia caused by SARS-CoV-2.

methodsWe searched five medical databases including two Chinese and three English databases for all published articles on COVID-19 since the outbreak. A random-effects model was designed, and the imaging and clinical data from all studies were collected for meta-analysis.

resultsOverall, 31 articles and 46 959 patients were included, including 10 English articles and 21 Chinese articles. The results of meta-analysis showed that the most common clinical manifestations were fever (87.3%; 0.838-0.909), cough (58.1%; 0.502-0.660), dyspnea (38.3%; 0.246-0.520), muscle soreness or fatigue (35.5%; 0.253-0.456), and chest distress (31.2%; -0.024 to 0.648). The main imaging findings were bilateral pneumonia (75.7%; 0.639-0.871) and ground-glass opacification (69.9%; 0.602-0.796). Among the patients, the incidence that required intensive care unit (ICU) was (29.3%; 0.190-0.395), the incidence with acute respiratory distress syndrome was (28.8%; 0.147-0.429), the incidence with multiple organ dysfunction syndrome was (8.5%; -0.008 to 0.179), and the case fatality rate of patients with COVID-19 was (6.8%; 0.044-0.093).

conclusionCOVID-19 is a new clinical infectious disease that mainly causes bilateral pneumonia and lung function deteriorates rapidly. Nearly a third of patients need to be admitted to the ICU, and patients are likely to present respiratory failure or even death.

Indexed as

AdultCOVID-19FemaleHumansLungMaleMiddle AgedRespiratory InsufficiencyTomography, X-Ray Computed2019 novel coronavirus pneumoniaclinical featuresimaging findingSARS-CoV-2

Identifiers

PMID32242947
PMCPMC7228215
OpenAlexW3014344637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.