Evidence map›Paper›PMID 32242475›Full record

ArticleJournal of the American Heart Association2020

Right Ventricular Strain Predicts Structural Disease Progression in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy.

Nitin Malik, Sithu Win, Cynthia A James, Shelby Kutty, Monica Mukherjee, Nisha A Gilotra, Crystal Tichnell, Brittney Murray, Julia Agafonova, Harikrishna Tandri and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. State-of-the-Art in Echocardiographic Strain Imaging of Arrhythmogenic Cardiomyopathy.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Fenotypic expressions and clinical manifestations of arrhythmogenic cardiomyopathy.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  9. Arrhythmogenic Right Ventricular Cardiomyopathy Presenting With VT Electrical Storm.Journal of community hospital internal medicine perspectives · 2025
    Article
  10. Article
  11. Review
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  13. Review
  14. Article
  15. Article
  16. Arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Nitin MalikJohns Hopkins University Baltimore MD.
Sithu WinJohns Hopkins University Baltimore MD.
Cynthia A JamesJohns Hopkins University Baltimore MD.
Shelby KuttyJohns Hopkins University Baltimore MD.
Monica MukherjeeJohns Hopkins University Baltimore MD.
Nisha A GilotraJohns Hopkins University Baltimore MD.
Crystal TichnellJohns Hopkins University Baltimore MD.
Brittney MurrayJohns Hopkins University Baltimore MD.
Julia AgafonovaJohns Hopkins University Baltimore MD.
Harikrishna TandriJohns Hopkins University Baltimore MD.
Hugh CalkinsJohns Hopkins University Baltimore MD.
Allison G HaysJohns Hopkins University Baltimore MD.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited condition associated with ventricular arrhythmias and myocardial dysfunction; however, limited data exist on identifying patients at highest risk. The purpose of the study was to determine whether measures of right ventricular (RV) dysfunction on echocardiogram including RV strain were predictive of structural disease progression in ARVC. Methods and Results A retrospective analysis of serial echocardiograms from 40 patients fulfilling 2010 task force criteria for ARVC was performed to assess structural progression defined by an increase in proximal RV outflow tract dimensions (parasternal short or long axis) or decrease in RV fractional area change. Echocardiograms were analyzed for RV free-wall peak longitudinal systolic strain using 2-dimensional speckle tracking. Risk of structural progression and 5-year change in RV outflow tract measurements were compared with baseline RV strain. Of the 40 ARVC patients, 61% had structural progression with an increase in the mean parasternal short-axis RV outflow tract dimension from 36.2 to 38.5 mm (

Indexed as

Myocardial ContractionVentricular Function, RightAdultArrhythmogenic Right Ventricular DysplasiaBaltimoreDisease ProgressionEchocardiographyFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesVentricular Dysfunction, RightYoung Adultarrhythmogenic right ventricular cardiomyopathyechocardiographystrain imaging

Identifiers

PMID32242475
PMCPMC7428652
OpenAlexW3014718631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.