ArticleEuropean child & adolescent psychiatry2021
Prenatal and perinatal factors associated with ADHD risk in schoolchildren: EPINED epidemiological study.
Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Two meta-analyses of the association between atopic diseases and core symptoms of attention deficit hyperactivity disorder.Scientific reports · 2022Pooled it
- Maternal Hypertensive Pregnancy Disorders and Mental and Behavioral Disorders in the Offspring: a Review.Current hypertension reports · 2021Pooled it
- Brain-Behavior Relationships: Neural Mechanisms of Impulsivity and Compulsivity in Neuropsychiatric Disorders.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2025Review
- Maternal dietary patterns and offspring behavioral problems.Pediatric research · 2025Article
- Expanding diversity in developmental profiles of very-low-birth-weight infants during 6 years after birth.Scientific reports · 2025Article
- P300 event-related potentials as diagnostic biomarkers for attention deficit hyperactivity disorder in children.Frontiers in psychiatry · 2025Article
- Prenatal Tobacco Exposure and Behavioral Disorders in Children and Adolescents: Systematic Review and Meta-Analysis.Pediatric reports · 2024Review
- The association between bisphenol a exposure and attention deficit hyperactivity disorder in children: a meta-analysis of observational studies.Reviews on environmental health · 2024Review
- Preterm or early term birth and risk of attention-deficit/hyperactivity disorder: a national cohort and co-sibling study.Annals of epidemiology · 2023Article
- Circulating Levels of Short-Chain Fatty Acids during Pregnancy and Infant Neurodevelopment.Nutrients · 2022Article
- Do Children with Attention-Deficit/Hyperactivity Disorder Follow a Different Dietary Pattern than That of Their Control Peers?Nutrients · 2022Article
- Psychometric Properties of ADHD Rating Scale-5 for Children and Adolescents in Sudan-School Version.Frontiers in psychology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The aim of this study is to assess the relationship between pre- and perinatal factors and ADHD in a sample of scholars exploring differences between ADHD presentations and spectrum of severity. A total of 6720 scholars (aged 3-4 and 10-11) participated in a double-phase epidemiologic cross-sectional study (Epidemiological Study of Neurodevelopmental Disorders, EPINED), and a sample of 646 scholars (ADHD risk, ASD risk and controls without risk) were individually assessed in the second phase of the study. The ADHD diagnosis, based on DSM-5 criteria, was performed with the Kiddie-Schedule for Affective Disorders & Schizophrenia, Present & Lifetime Version. Associations for the different ADHD presentations between prenatal, perinatal and postnatal factors and ADHD (n = 168), subclinical ADHD (n = 88) and non-ADHD (n = 310) were analysed. Logistic regression models showed that gestational diabetes (p = 0.012), instrumental delivery (p = 0.011), family history of psychopathology (p = 0.033) and maternal ADHD phenotype (p = 0.023) were associated with ADHD. These factors were related to the hyperactive-impulsive and combined presentations, but they were not related to the inattentive presentation. Maternal weight gain was associated with subclinical ADHD. In conclusion, metabolic disorder in the pregnancy, difficulties in childbirth and specific family phenotype were related to ADHD, specifically with hyperactive-impulsive presentation, but not in subclinical ADHD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.