SynthesisEpidemiologic reviews2020
Prescription Drug Monitoring Programs and Prescription Opioid-Related Outcomes in the United States.
Synthesis in Epidemiologic reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cost-effective interventions to prevent prescription drug misuse: a systematic review.Frontiers in public health · 2025Pooled it
- Efficacy of interventions targeted at physician prescribers of opioids for chronic non-cancer pain: an overview of systematic reviews.BMC medicine · 2024Pooled it
- Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Effect of Integrating Access to a Prescription Drug Monitoring Program Within the Electronic Health Record on the Frequency of Queries by Primary Care Clinicians: A Cluster Randomized Clinical Trial.JAMA health forum · 2022Trial
- Opioid Dispensing Volume and Per-Patient Intensity in Sickle Cell Disease.JAMA network open · 2026Article
- Evaluation of Loma Linda University Health clinicians' beliefs, knowledge and experiences regarding pain management.BMC health services research · 2026Article
- Impact of Prescription Drug Monitoring Programs on Postpartum Opioid Prescribing Practices.Health services research · 2026Article
- Do Must-Access Prescription Drug Monitoring Programs (PDMPs) Affect Pain and Impairment Outcomes in Older Adults?Medical care research and review : MCRR · 2026Article
- Article
- Emergency department opioid prescribing trends among provider types: an analysis of the NHAMCS, 2019-2021.Internal and emergency medicine · 2026Observational
- Healthcare consumers' perceptions and experiences of an Australian prescription drug monitoring program: a cross-sectional survey.Frontiers in digital health · 2026Article
- Perceptual Discrepancies of Opioid Analgesics and Psychotropic Drugs: A Cross-Sectional Study of Korean Patients and Physicians.Journal of clinical medicine · 2025Article
- Improving Policy Evaluations Of The Opioid Crisis.Health affairs (Project Hope) · 2025Article
- Prescription opioid supply-restricting policies and hospital use by people prescribed opioid medications, Victoria, 2018-22: a controlled interrupted time series analysis.The Medical journal of Australia · 2025Article
- Cannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients.JAMA health forum · 2025Article
- The Combined Relationship of Prescription Drug Monitoring Program Enactment and Medical Cannabis Laws with Chronic Pain-Related Healthcare Visits.Journal of general internal medicine · 2025Article
- Effects of state opioid prescribing laws on rates of fatal crashes in the USA.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2025Article
- Opioid Prescriptions for US Patients Undergoing Long-Term Dialysis or with Kidney Transplant from 2011 to 2020.Journal of the American Society of Nephrology : JASN · 2025Article
- State-level factors associated with implementation of prescription drug monitoring program integration and mandatory use policies, United States, 2009-2020.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- A theoretical explanation of naloxone provision among primary care physicians and community pharmacists in Tennessee.Research in social & administrative pharmacy : RSAP · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Prescription drug monitoring programs (PDMPs) are a crucial component of federal and state governments' response to the opioid epidemic. Evidence about the effectiveness of PDMPs in reducing prescription opioid-related adverse outcomes is mixed. We conducted a systematic review to examine whether PDMP implementation within the United States is associated with changes in 4 prescription opioid-related outcome domains: opioid prescribing behaviors, opioid diversion and supply, opioid-related morbidity and substance-use disorders, and opioid-related deaths. We searched for eligible publications in Embase, Google Scholar, MEDLINE, and Web of Science. A total of 29 studies, published between 2009 and 2019, met the inclusion criteria. Of the 16 studies examining PDMPs and prescribing behaviors, 11 found that implementing PDMPs reduced prescribing behaviors. All 3 studies on opioid diversion and supply reported reductions in the examined outcomes. In the opioid-related morbidity and substance-use disorders domain, 7 of 8 studies found associations with prescription opioid-related outcomes. Four of 8 studies in the opioid-related deaths domain reported reduced mortality rates. Despite the mixed findings, emerging evidence supports that the implementation of state PDMPs reduces opioid prescriptions, opioid diversion and supply, and opioid-related morbidity and substance-use disorder outcomes. When PDMP characteristics were examined, mandatory access provisions were associated with reductions in prescribing behaviors, diversion outcomes, hospital admissions, substance-use disorders, and mortality rates. Inconsistencies in the evidence base across outcome domains are due to analytical approaches across studies and, to some extent, heterogeneities in PDMP policies implemented across states and over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.