ArticleThe journal of nutrition, health & aging2020
Handgrip Strength and Timed Up-and-Go (TUG) Test are Predictors of Short-Term Mortality among Elderly in a Population-Based Cohort in Singapore.
Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Effects of oral oligopeptide preparation and exercise intervention in older people with sarcopenia: a randomized controlled trial.BMC geriatrics · 2024Trial
- Impact of changes in sarcopenia status on incident cardiovascular disease and mortality in older adults.Scientific reports · 2026Article
- Association between sleep duration from midlife and the risk of physical frailty in late life.Scientific reports · 2026Article
- Association between maximal lower leg strength and static and dynamic balance as well as gait velocity in older adults.Frontiers in aging · 2026Article
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- Quality of Life, Physical Activity, and Mental and Physical Health Status in Croatian Middle-Aged and Elderly Population.Healthcare (Basel, Switzerland) · 2025Article
- Utilizing the Timed Up and Go Test to Predict Five-Year Mortalities Among Older Cardiovascular Inpatients: A Prospective Cohort Study.Reviews in cardiovascular medicine · 2025Article
- Article
- Evaluating the Effects of Sensorimotor Training on the Physical Capacities of Older People.European journal of investigation in health, psychology and education · 2025Article
- Relationship between handgrip strength and timed up-and-go test on hospitalization costs in older adults: a population-based study.BMC public health · 2025Article
- Intake of vegetables and fruits at midlife and the risk of physical frailty in later life.The journal of nutrition, health & aging · 2024Article
- Sex-Specific Variations in Glycated Hemoglobin Responses to Structured Exercise in Type 2 Diabetes: Healthcare Implications of Walking and Strength Training on Glycemic Control.Healthcare (Basel, Switzerland) · 2024Article
- Reproductive factors and risk of physical frailty among Chinese women living in Singapore.The journal of nutrition, health & aging · 2024Article
- Higher handgrip strength is linked to higher salience ventral attention functional network segregation in older adults.Communications biology · 2024Article
- Associations of Frailty, Defined Using Three Different Instruments, with All-Cause Mortality in a Tertiary Outpatient Clinic in Turkiye.International journal of general medicine · 2024Article
- Biological ageing and the risk of decreased handgrip strength among community-dwelling older adult Indians: a cross-sectional study.BMC geriatrics · 2023Article
- Development of a Machine Learning-Based Model to Predict Timed-Up-and-Go Test in Older Adults.Geriatrics (Basel, Switzerland) · 2023Article
- Mortality Associations With DNA Methylation-Based Biological Aging and Physical Functioning Measures Across a 20-Year Follow-up Period.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Age-Related Decline in Cervical Proprioception and Its Correlation with Functional Mobility and Limits of Stability Assessed Using Computerized Posturography: A Cross-Sectional Study Comparing Older (65+ Years) and Younger Adults.Healthcare (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors.
Funding
Abstract
objectivesAsian studies on how physical tests predict short-term mortality in elderly are scarce. We assessed handgrip strength and timed-up-and-go (TUG) as such predictors among elderly Chinese in Singapore.
designProspective cohort study.
settingCommunity-dwelling Chinese elderly in Singapore.
participantsWe used data from 13,789 subjects in the prospective, population-based Singapore Chinese Health Study, who had a mean age of 74 (range 63 to 97) years at time of measurements. MEASUREMENTS: Subjects underwent assessment for handgrip strength and TUG. They were followed for mortality via linkage with nationwide death registry through 2018.
resultsIn multivariable analyses, handgrip strength was inversely associated with risk of mortality in a dose-dependent manner: the hazard ratio (HR) [95% confidence interval (CI)] comparing extreme quartiles was 2.05 (1.44-2.90) (Ptrend<0.001). TUG was positively associated with mortality in a stepwise manner: the HR (95% CI) comparing extreme quartiles was 3.08 (2.17-4.38) (Ptrend<0.001). Compared to those with stronger handgrip and faster TUG, participants who either had weaker handgrip or slower TUG had a significant 1.59 to 2.11 fold increase in risk of mortality; while the HR (95% CI) for those who had both weaker handgrip and slower TUG was 3.93 (3.06-5.05). In time-dependent receiver operating characteristic curves, adding handgrip strength and TUG time to a Cox model containing sociodemographic and lifestyle factors, comorbidities, and body measurements significantly improved the area under the curve for the prediction of mortality from 0.5 to 2 years (P≤0.001).
conclusionAmong elderly in a Chinese population, handgrip strength and TUG test were strong and independent predictors of short-term mortality.
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