Evidence map›Paper›PMID 32241911›Full record

ArticleThe Journal of biological chemistry2020

The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding.

Urmimala Basu, Nandini Mishra, Mohammed Farooqui, Jiayu Shen, Laura C Johnson, Smita S Patel

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Urmimala BasuDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0003-4035-1246
Nandini MishraDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Mohammed FarooquiDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Jiayu ShenDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0001-8447-9378
Laura C JohnsonDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Smita S PatelDepartment of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854 patelss@rutgers.edu.ORCID 0000-0002-2523-4933
Rutgers, The State University of New Jersey · US

Funding

Mechanistic studies of nucleic acid enzymes involved in DNA replication, transcription, and innate immunity.R35GM118086 · NIGMS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SMITA S PATEL · 2016 to 2026
$8.9M
NIGMS NIH HHS R35 GM118086
6 · The paper itself

Abstract

The structurally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of mitochondrial RNA polymerases in

Indexed as

Transcription, GeneticDNA-Directed RNA PolymerasesDNA, FungalDNA, MitochondrialMitochondrial ProteinsProtein DomainsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsDNA-Directed RNA PolymerasesDNA, FungalDNA, MitochondrialMitochondrial ProteinsMTF1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factorsautoinhibitionfluorescence anisotropymitochondriamitochondrial RNA polymerasemitochondrial transcription factorsMtf1protein–DNA interactionRNA polymeraseTFB2Mtranscriptional coactivator

Identifiers

PMID32241911
PMCPMC7242694
OpenAlexW3015141197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.