ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
The Neural Origin of Nociceptive-Induced Gamma-Band Oscillations.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 50 citations in OpenAlex.
- Article
- Integrating multidimensional nociceptive-related cortical features for unsupervised assessment of anesthesia states in rats.iScience · 2026Article
- EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation.Scientific reports · 2025Article
- The Investigation of the Relationship Between Individual Pain Perception, Brain Electrical Activity, and Facial Expression Based on Combined EEG and Facial EMG Analysis.Journal of pain research · 2025Article
- Decoding pain's neural rhythm: Gamma oscillation mechanisms, therapeutic modulation, and translational challenges in pain management.Frontiers in neuroscience · 2025Review
- Advances and challenges in neuroimaging-based pain biomarkers.Cell reports. Medicine · 2024Review
- A distinct neuronal ensemble of prelimbic cortex mediates spontaneous pain in rats with peripheral inflammation.Nature communications · 2024Article
- Ventral Hippocampal CA1 Pyramidal Neurons Encode Nociceptive Information.Neuroscience bulletin · 2024Article
- Deciphering Authentic Nociceptive Thalamic Responses in Rats.Research (Washington, D.C.) · 2024Article
- Distinct neocortical mechanisms underlie human SI responses to median nerve and laser-evoked peripheral activation.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Pain-preferential thalamocortical neural dynamics across species.Nature human behaviour · 2024Article
- Interindividual variability and individual stability of pain- and touch-related neuronal gamma oscillations.Journal of neurophysiology · 2023Article
- Dynamic peripheral nerve stimulation can produce cortical activation similar to punctate mechanical stimuli.Frontiers in human neuroscience · 2023Article
- Somatosensory cortical signature of facial nociception and vibrotactile touch-induced analgesia.Science advances · 2022Article
- Early Life Pain Experience Changes Adult Functional Pain Connectivity in the Rat Somatosensory and the Medial Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Cholinergic basal forebrain nucleus of Meynert regulates chronic pain-like behavior via modulation of the prelimbic cortex.Nature communications · 2022Article
- The role of gamma oscillations in central nervous system diseases: Mechanism and treatment.Frontiers in cellular neuroscience · 2022Review
- Cortical interaction of bilateral inputs is similar for noxious and innocuous stimuli but leads to different perceptual effects.Experimental brain research · 2021Article
- Neocortical circuits in pain and pain relief.Nature reviews. Neuroscience · 2021Review
- The Prediction of Acute Postoperative Pain Based on Neural Oscillations Measured before the Surgery.Neural plasticity · 2021Article
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3 authors at 3 institutions in 3 countries.
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Abstract
Gamma-band oscillations (GBOs) elicited by transient nociceptive stimuli are one of the most promising biomarkers of pain across species. Still, whether these GBOs reflect stimulus encoding in the primary somatosensory cortex (S1) or nocifensive behavior in the primary motor cortex (M1) is debated. Here we recorded neural activity simultaneously from the brain surface as well as at different depths of the bilateral S1/M1 in freely-moving male rats receiving nociceptive stimulation. GBOs measured from superficial layers of S1 contralateral to the stimulated paw not only had the largest magnitude, but also showed the strongest temporal and phase coupling with epidural GBOs. Also, spiking of superficial S1 interneurons had the strongest phase coherence with epidural GBOs. These results provide the first direct demonstration that scalp GBOs, one of the most promising pain biomarkers, reflect neural activity strongly coupled with the fast spiking of interneurons in the superficial layers of the S1 contralateral to the stimulated side.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.