Evidence map›Paper›PMID 32241803›Full record

ArticleGenes & development2020

Positive autofeedback regulation of

Bishakha Mona, Juan Villarreal, Trisha K Savage, Rahul K Kollipara, Brooke E Boisvert, Jane E Johnson

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Central neural circuits underlying itch sensation.Nature reviews. Neuroscience · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bishakha MonaDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Juan VillarrealDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Trisha K SavageDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Rahul K KolliparaMcDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Brooke E BoisvertDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Jane E JohnsonDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.ORCID 0000-0002-8605-2746
The University of Texas Southwestern Medical Center · USSouthwestern Medical Center · US

Funding

BHLH TRANSCRIPTION FACTORS IN NEURAL DEVELOPMENTR01HD037932 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI JOHNSON, JANE E · 2000 to 2015
$4.9M
Transcription Factor Control of Neuronal DiversityR37HD091856 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI Jane E Johnson · 2017 to 2026
$4.7M
NICHD NIH HHS R01 HD037932NICHD NIH HHS R37 HD091856
6 · The paper itself

Abstract

Peripheral somatosensory input is modulated in the dorsal spinal cord by a network of excitatory and inhibitory interneurons. PTF1A is a transcription factor essential in dorsal neural tube progenitors for specification of these inhibitory neurons. Thus, mechanisms regulating

Indexed as

AnimalsCRISPR-Cas SystemsEnhancer Elements, GeneticFeedback, PhysiologicalGene Expression RegulationMiceMutationNeuronsPruritusSpinal CordTranscription Factorstranscription factor PTF1Transcription FactorsautoregulationbHLH transcription factorcell fate specificationinhibitory neuronitchneuronal identitysomatosensoryspinal cord developmenttranscriptional control

Identifiers

PMID32241803
PMCPMC7197352
OpenAlexW3015127073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.