ArticleBMJ (Clinical research ed.)2020
Infectious diseases in children and adolescents in China: analysis of national surveillance data from 2008 to 2017.
Article in BMJ (Clinical research ed.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 5 of them syntheses that pooled it.
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Who cites it
95 citing papers in PubMed, 5 syntheses or guidelines pooled it, 165 citations in OpenAlex.
- Human papillomavirus and vaccine knowledge, willingness, and uptake among university students: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from China, 1980-2015.BMC infectious diseases · 2024Pooled it
- Non-pharmaceutical interventions for COVID-19 reduced the incidence of infectious diseases: a controlled interrupted time-series study.Infectious diseases of poverty · 2023Pooled it
- Meteorological Factors Affecting Infectious Diarrhea in Different Climate Zones of China.International journal of environmental research and public health · 2022Pooled it
- The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A review of the current global status.Journal of infection and public health · 2020Pooled it
- The Effect of a Video-Assisted Health Education Program Followed by Peer Education on the Health Literacy of COVID-19 and Other Infectious Diseases Among School Children: Quasi-Randomized Controlled Trial.JMIR human factors · 2024Trial
- Elevated nil values in TB-IGRA: a potential diagnostic clue for pediatric histiocytic necrotizing lymphadenitis.Pediatric rheumatology online journal · 2026Article
- Cost-effectiveness analysis of 23-valent pneumococcal polysaccharide vaccine for adults in China.Infectious medicine · 2026Article
- Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells.International journal of molecular medicine · 2026Article
- Impact of hand hygiene on infection-related symptoms in school-aged children: a cross-sectional study on the moderating effect of depression.BMC pediatrics · 2026Article
- Under-5 mortality of infectious diseases in 204 countries between 1990 and 2021.Translational pediatrics · 2026Article
- Spatiotemporal heterogeneity and influencing factors of hepatitis B in China: a 17-year national surveillance analysis.BMC public health · 2026Article
- Epidemiological characteristics and spatio-temporal analysis of bacillary dysentery in Shaanxi Province, China, 2005-2024.BMC infectious diseases · 2026Article
- Article
- Epidemiological characteristics and LSTM-based simulation of mumps incidence in Ningbo, China from 2005 to 2024.BMC public health · 2026Article
- Epidemiological Characteristics of Mumps Under Different Immunization Strategies in Henan Province.Vaccines · 2026Article
- Assessment of childhood disease patterns in outpatient settings: a retrospective study from 2016 to 2020.Frontiers in pediatrics · 2026Article
- The impact of El Niño-Southern Oscillation on the incidence of infectious diarrhea in China: insights from a 15-year national surveillance analysis.Frontiers in public health · 2026Article
- The temporal trends of incidence, prevalence, mortality, and disability-adjusted life years of inflammatory bowel disease in the Chinese population aged 0-54 years and prediction to 2030.Frontiers in medicine · 2026Article
- Life-course restructuring of infectious mortality in China, 2004-2021: a national surveillance study.Frontiers in public health · 2026Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo outline which infectious diseases in the pre-covid-19 era persist in children and adolescents in China and to describe recent trends and variations by age, sex, season, and province.
designNational surveillance studies, 2008-17.
setting31 provinces in mainland China.
participants4 959 790 Chinese students aged 6 to 22 years with a diagnosis of any of 44 notifiable infectious diseases. The diseases were categorised into seven groups: quarantinable; vaccine preventable; gastrointestinal and enteroviral; vectorborne; zoonotic; bacterial; and sexually transmitted and bloodborne.
main outcome measuresDiagnosis of, and deaths from, 44 notifiable infectious diseases.
resultsFrom 2008 to 2017, 44 notifiable infectious diseases were diagnosed in 4 959 790 participants (3 045 905 males, 1 913 885 females) and there were 2532 deaths (1663 males, 869 females). The leading causes of death among infectious diseases shifted from rabies and tuberculosis to HIV/AIDS, particularly in males. Mortality from infectious diseases decreased steadily from 0.21 per 100 000 population in 2008 to 0.07 per 100 000 in 2017. Quarantinable conditions with high mortality have effectively disappeared. The incidence of notifiable infectious diseases in children and adolescents decreased from 280 per 100 000 in 2008 to 162 per 100 000 in 2015, but rose again to 242 per 100 000 in 2017, largely related to mumps and seasonal influenza. Excluding mumps and influenza, the incidence of vaccine preventable diseases fell from 96 per 100 000 in 2008 to 7 per 100 000 in 2017. The incidence of gastrointestinal and enterovirus diseases remained constant, but typhoid, paratyphoid, and dysentery continued to decline. Vectorborne diseases all declined, with a particularly noticeable reduction in malaria. Zoonotic infections remained at low incidence, but there were still unpredictable outbreaks, such as pandemic A/H1N1 2009 influenza. Tuberculosis remained the most common bacterial infection, although cases of scarlet fever doubled between 2008 and 2017. Sexually transmitted diseases and bloodborne infections increased significantly, particularly from 2011 to 2017, among which HIV/AIDS increased fivefold, particularly in males. Difference was noticeable between regions, with children and adolescents in western China continuing to carry a disproportionate burden from infectious diseases.
conclusionsChina's success in infectious disease control in the pre-covid-19 era was notable, with deaths due to infectious diseases in children and adolescents aged 6-22 years becoming rare. Many challenges remain around reducing regional inequalities, scaling-up of vaccination, prevention of further escalation of HIV/AIDS, renewed efforts for persisting diseases, and undertaking early and effective response to highly transmissible seasonal and unpredictable diseases such as that caused by the novel SARS-CoV-2 virus.
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