ArticleBritish journal of anaesthesia2020
Calabadion 1 selectively reverses respiratory and central nervous system effects of fentanyl in a rat model.
Article in British journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 36 citations in OpenAlex.
- Molecular recognition properties of water-soluble Prism[5]arene towards drugs of abuse.Supramolecular chemistry · 2026Article
- Tetrachloroanthracene Walled Glycoluril Dimer Undergoes Self-Association and 1:1, 2:2, and 1:3 Host•Guest Binding.Supramolecular chemistry · 2025Article
- Current and Developing Approaches for Facilitating Emergence from General Anesthesia.Anesthesiology · 2025Review
- Aromatic Wall Extension of Glycoluril-Derived Molecular Clips Enhances Binding of Planar Aromatic Dyes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Developing novel drugs to reverse neuromuscular block: do we need them?British journal of anaesthesia · 2025Article
- Acyclic cucurbit[Beilstein journal of organic chemistry · 2025Article
- Insoluble methylene-bridged glycoluril dimers as sequestrants for dyes.Beilstein journal of organic chemistry · 2025Article
- Evaluation of Subetadex-α-methyl, a Polyanionic Cyclodextrin Scaffold, as a Medical Countermeasure against Fentanyl and Related Opioids.ACS central science · 2024Article
- Supramolecular nanotherapeutics based on cucurbiturils.Journal of nanobiotechnology · 2024Review
- Insoluble Acyclic Cucurbit[n]uril-Type Receptors Capture Iodine from the Vapor Phase.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- The Influence of Acid-Base Balance on Anesthetic Muscle Relaxants: A Comprehensive Review on Clinical Applications and Mechanisms.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Nanotherapeutics for Alleviating Anesthesia-Associated Complications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- IUPHAR Review: New strategies for medications to treat substance use disorders.Pharmacological research · 2024Review
- Goofball Polypharmacy.The Journal of pharmacology and experimental therapeutics · 2024Article
- Article
- Application of Magnetocardiography to Screen for Inflammatory Cardiomyopathy and Monitor Treatment Response.Journal of the American Heart Association · 2023Article
- Evaluation of polyanionic cyclodextrins as high affinity binding scaffolds for fentanyl.Scientific reports · 2023Article
- Trailblazing through the Opioid Epidemic. Will Science Prevail?Translational perioperative and pain medicine · 2023Article
- Unique Pharmacology, Brain Dysfunction, and Therapeutic Advancements for Fentanyl Misuse and Abuse.Neuroscience bulletin · 2022Review
- Anthracene-Walled Acyclic CB[n] Receptors: in vitro and in vivo Binding Properties toward Drugs of Abuse.ChemMedChem · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundWe hypothesised that Calabadion 1, an acyclic cucurbit[n]uril molecular container, reverses fentanyl-induced respiratory depression and dysfunction of the CNS.
methodsExperiments were conducted in male Sprague-Dawley rats. A constant-rate i.v. infusion of fentanyl (12.5 or 25 μg kg
resultsCalabadion 1 reversed fentanyl-induced respiratory depression across the endpoints minute ventilation, pH, and Paco
conclusionsCalabadion 1 selectively and dose dependently reversed the respiratory system and CNS side-effects of fentanyl.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.