Evidence map›Paper›PMID 32241474›Full record

ArticlePoultry science2020

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus.

Peng Sun, Ning Cui, Linqing Liu, Shuai Su, Ziqiang Cheng, Ruiai Chen, Yanpeng Li, Zhizhong Cui

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Peng SunShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention; College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Ning CuiShandong Key Laboratory of Animal Disease Control & Breeding; Institute of Animal Husbandry and Veterinary, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Linqing LiuChina Animal Disease Control Center, Beijing, 100125 China.
Shuai SuShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention; College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China. Electronic address: ssu6307@163.com.
Ziqiang ChengShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention; College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Ruiai ChenCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong 510642, China. Electronic address: chensa727@126.com.
Yanpeng LiZhaoqing Institute of Biotechnology Co., Ltd., Zhaoqing, Guangdong 526238, China.
Zhizhong CuiShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention; College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Shandong Agricultural University · CNShandong Center for Disease Control and Prevention · CNChina Animal Disease Control Center · CNShandong Academy of Agricultural Sciences · CNSouth China Agricultural University · CNZhaoqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SC9-2 is a recombinant Marek's disease virus (MDV) strain lacking the meq oncogene. Previous study demonstrated that SC9-2 virus provides good protection against challenge with a very virulent MDV rMd5, but it induces immunosuppressive effects in specific pathogen-free (SPF) chickens. In the present study, SC9-2 was serially passaged on chicken embryo fibroblast (CEF) cell cultures. The pathogenicity and immune efficacy of SC9-2/10

Indexed as

ChickensAnimalsHerpesvirus 2, GallidMarek DiseaseMarek Disease VaccinesMicroorganisms, Genetically-ModifiedOncogene Proteins, ViralPoultry DiseasesSpecific Pathogen-Free OrganismsEco-Q protein, Gallid herpesvirus 2Marek Disease VaccinesOncogene Proteins, Viralattenuationcell culture passageimmune efficacyMarek's disease virusmeq gene

Identifiers

PMID32241474
PMCPMC7587640
OpenAlexW3002099389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.