Evidence map›Paper›PMID 32241371›Full record

Trial reportJournal of the American College of Cardiology2020

Yoga-Based Cardiac Rehabilitation After Acute Myocardial Infarction: A Randomized Trial.

Dorairaj Prabhakaran, Ambalam M Chandrasekaran, Kalpana Singh, Bishav Mohan, Kaushik Chattopadhyay, Davinder S Chadha, Prakash C Negi, Prabhavathi Bhat, Kanchanahalli S Sadananda, Vamadevan S Ajay and 18 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 7 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 7 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Home-based versus centre-based cardiac rehabilitation.The Cochrane database of systematic reviews · 2023
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  5. Exercise-based cardiac rehabilitation for coronary heart disease.The Cochrane database of systematic reviews · 2021
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  8. Trial
  9. Review
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  13. Safety, feasibility and impact of a 12-week yoga program in adults Fontan patients: a pilot study.International journal of cardiology. Congenital heart disease · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 14 institutions in 3 countries.

Dorairaj PrabhakaranCentre for Chronic Disease Control, New Delhi, India; Public Health Foundation of India, New Delhi, India; London School of Hygiene and Tropical Medicine, London, United Kingdom; Rollins School of Public Health, Emory University, Atlanta, Georgia. Electronic address: dprabhakaran@ccdcindia.org.
Ambalam M ChandrasekaranCentre for Chronic Disease Control, New Delhi, India.
Kalpana SinghCentre for Chronic Disease Control, New Delhi, India.
Bishav MohanDayanand Medical College, Ludhiana, India.
Kaushik ChattopadhyayLondon School of Hygiene and Tropical Medicine, London, United Kingdom; The University of Nottingham, Nottingham, United Kingdom.
Davinder S ChadhaCommand Hospital, Bengaluru, India.
Prakash C NegiIndira Gandhi Medical College, Shimla, India.
Prabhavathi BhatSri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, India.
Kanchanahalli S SadanandaSri Jayadeva Institute of Cardiovascular Sciences and Research, Mysuru, India.
Vamadevan S AjayCentre for Chronic Disease Control, New Delhi, India; Public Health Foundation of India, New Delhi, India.
Kavita SinghCentre for Chronic Disease Control, New Delhi, India.
Pradeep A PraveenCentre for Chronic Disease Control, New Delhi, India; All India Institute of Medical Sciences, New Delhi, India.
Raji DevarajanCentre for Chronic Disease Control, New Delhi, India.
Dimple KondalCentre for Chronic Disease Control, New Delhi, India.
Divya SoniCentre for Chronic Disease Control, New Delhi, India.
Poppy MallinsonLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Subhash C ManchandaSir Ganga Ram Hospital, New Delhi, India.
Kushal MadanSir Ganga Ram Hospital, New Delhi, India.
Alun D HughesMRC Unit for Lifelong Health and Ageing at University College London, London, United Kingdom; Imperial College London, London, United Kingdom.
Nishi ChathurvediMRC Unit for Lifelong Health and Ageing at University College London, London, United Kingdom; Imperial College London, London, United Kingdom.
Ian RobertsLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Shah EbrahimLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Kolli S ReddyPublic Health Foundation of India, New Delhi, India.
Nikhil TandonAll India Institute of Medical Sciences, New Delhi, India.
Stuart PocockLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Ambuj RoyAll India Institute of Medical Sciences, New Delhi, India.
Sanjay KinraLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Yoga-CaRe Trial Investigators
Centre for Chronic Disease Control · INLondon School of Hygiene & Tropical Medicine · GBAll India Institute of Medical Sciences · INSir Ganga Ram Hospital · INPublic Health Foundation of India · INSri Jayadeva Institute of Cardiovascular Sciences and Research · INCommand Hospital · INDayanand Medical College & Hospital · INEmory University · USIndira Gandhi Medical College · INMRC Unit for Lifelong Health and Ageing · GBUniversity College London · GBImperial College London · GBUniversity of Nottingham · GB

Funding

Developing and testing Collaborative Quality ImProvement initiative (C-QIP) for prevention of cardiovascular disease in IndiaK43TW011164 · FIC · PUBLIC HEALTH FOUNDATION OF INDIA · PI SINGH, KAVITA · 2019 to 2023
$342k
FIC NIH HHS K43 TW011164Medical Research Council MR/J000175/1
6 · The paper itself

Abstract

backgroundGiven the shortage of cardiac rehabilitation (CR) programs in India and poor uptake worldwide, there is an urgent need to find alternative models of CR that are inexpensive and may offer choice to subgroups with poor uptake (e.g., women and elderly).

objectivesThis study sought to evaluate the effects of yoga-based CR (Yoga-CaRe) on major cardiovascular events and self-rated health in a multicenter randomized controlled trial.

methodsThe trial was conducted in 24 medical centers across India. This study recruited 3,959 patients with acute myocardial infarction with a median and minimum follow-up of 22 and 6 months. Patients were individually randomized to receive either a Yoga-CaRe program (n = 1,970) or enhanced standard care involving educational advice (n = 1,989). The co-primary outcomes were: 1) first occurrence of major adverse cardiovascular events (MACE) (composite of all-cause mortality, myocardial infarction, stroke, or emergency cardiovascular hospitalization); and 2) self-rated health on the European Quality of Life-5 Dimensions-5 Level visual analogue scale at 12 weeks.

resultsMACE occurred in 131 (6.7%) patients in the Yoga-CaRe group and 146 (7.4%) patients in the enhanced standard care group (hazard ratio with Yoga-CaRe: 0.90; 95% confidence interval [CI]: 0.71 to 1.15; p = 0.41). Self-rated health was 77 in Yoga-CaRe and 75.7 in the enhanced standard care group (baseline-adjusted mean difference in favor of Yoga-CaRe: 1.5; 95% CI: 0.5 to 2.5; p = 0.002). The Yoga-CaRe group had greater return to pre-infarct activities, but there was no difference in tobacco cessation or medication adherence between the treatment groups (secondary outcomes).

conclusionsYoga-CaRe improved self-rated health and return to pre-infarct activities after acute myocardial infarction, but the trial lacked statistical power to show a difference in MACE. Yoga-CaRe may be an option when conventional CR is unavailable or unacceptable to individuals. (A study on effectiveness of YOGA based cardiac rehabilitation programme in India and United Kingdom; CTRI/2012/02/002408).

Indexed as

YogaAdultCardiac RehabilitationFemaleHumansIndiaMaleMiddle AgedMyocardial InfarctionPatient Complianceacute myocardial infarctioncardiac rehabilitationcoronary artery diseaserehabilitationsecondary preventionyoga

Identifiers

PMID32241371
PMCPMC7132532
OpenAlexW3013093965

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.