Evidence map›Paper›PMID 32241300›Full record

ReviewJournal of biomedical science2020

Expedition to the missing link: Long noncoding RNAs in cardiovascular diseases.

Chih-Fan Yeh, Yu-Chen Eugene Chang, Cheng-Yuan Lu, Chin-Feng Hsuan, Wei-Tien Chang, Kai-Chien Yang

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of biomedical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  14. Article
  15. Role of long non-coding RNAs in adipogenesis: State of the art and implications in obesity and obesity-associated diseases.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Review
  16. Epigenetic Regulation of Autophagy in Cardiovascular Pathobiology.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chih-Fan YehGraduate Institute and Department of Pharmacology, National Taiwan University School of Medicine, No.1, Sec. 1, Ren-Ai Rd, 1150R, Taipei, Taiwan.
Yu-Chen Eugene ChangGraduate Institute and Department of Pharmacology, National Taiwan University School of Medicine, No.1, Sec. 1, Ren-Ai Rd, 1150R, Taipei, Taiwan.
Cheng-Yuan LuGraduate Institute and Department of Pharmacology, National Taiwan University School of Medicine, No.1, Sec. 1, Ren-Ai Rd, 1150R, Taipei, Taiwan.
Chin-Feng HsuanDivision of Cardiology, Department of Internal Medicine, E-Da Dachang Hospital, Kaohsiung, Taiwan.
Wei-Tien ChangDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Kai-Chien YangGraduate Institute and Department of Pharmacology, National Taiwan University School of Medicine, No.1, Sec. 1, Ren-Ai Rd, 1150R, Taipei, Taiwan. kcyang@ntu.edu.tw.
National Taiwan University Hospital · TWNational Taiwan University · TWE-Da Hospital · TW

Funding

Academia Sinica CRC108-P03College of Medicine, National Taiwan University 109L7872Ministry of Science and Technology, Taiwan 103-2320-B-002-068-MY2, 105-2628-B-002 -042-MY4, 108-2314-B-002-199-MY3National Health Research Institutes EX104-10418SCNational Health Research Institutes NHRI-EX109-10936SINational Taiwan University Hospital NTUH.106-P02, 105-CGN01, UN106-026, 106-N3740, VN106-12, 107-T02, 108-06, 109-07, UN107-019, 107-N4062, VN107-03, 108-T16, VN108-06, NTUH.108-P04, 108-N4198, 108-S4247, 109-S4576, 108-EDN03,
6 · The paper itself

Abstract

With the advances in deep sequencing-based transcriptome profiling technology, it is now known that human genome is transcribed more pervasively than previously thought. Up to 90% of the human DNA is transcribed, and a large proportion of the human genome is transcribed as long noncoding RNAs (lncRNAs), a heterogenous group of non-coding transcripts longer than 200 nucleotides. Emerging evidence suggests that lncRNAs are functional and contribute to the complex regulatory networks involved in cardiovascular development and diseases. In this article, we will review recent evidence on the roles of lncRNAs in the biological processes of cardiovascular development and disorders. The potential applications of lncRNAs as biomarkers and targets for therapeutics are also discussed.

Indexed as

Gene Expression ProfilingAnimalsBiomarkersCardiovascular DiseasesHumansMiceRatsRNA, Long NoncodingBiomarkersRNA, Long NoncodingCardiovascularDevelopmentDiseaseLong noncoding RNA

Identifiers

PMID32241300
PMCPMC7114803
OpenAlexW3014821816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.