ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020
SARS-CoV-2 Is Not Detectable in the Vaginal Fluid of Women With Severe COVID-19 Infection.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 115 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Vaginal Fluid for Covid-19 Positivity
Valuation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19
Who cites it
115 citing papers in PubMed, 7 syntheses or guidelines pooled it, 210 citations in OpenAlex.
- Impact of SARS-CoV-2 infection on clinical outcomes ofFrontiers in endocrinology · 2023Pooled it
- Absence of SARS-CoV-2 infection in the semen of men recovering from COVID-19 infection: An exploratory study and review of literature.Andrologia · 2021Pooled it
- Clinical Features and Outcome of SARS-CoV-2 Infection in Neonates: A Systematic Review.Journal of tropical pediatrics · 2021Pooled it
- Chest CT findings of coronavirus disease 2019 (COVID-19): A comprehensive meta-analysis of 9907 confirmed patients.Clinical imaging · 2021Pooled it
- Is liver involvement overestimated in COVID-19 patients? A meta-analysis.International journal of medical sciences · 2021Pooled it
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its effect on gametogenesis and early pregnancy.American journal of reproductive immunology (New York, N.Y. : 1989) · 2020Pooled it
- COVID-19 in pregnant women: A systematic review and meta-analysis.European journal of obstetrics, gynecology, and reproductive biology · 2020Pooled it
- The Multifaceted Impact of the SARS-CoV-2 Pandemic on Sexual Health, Function, and Behaviors: Implications for Public Health: A Scoping Review.Healthcare (Basel, Switzerland) · 2025Review
- How to Manage a Neonate Born from a SARS-CoV-2-Positive Mother: A Narrative Review.Pathogens (Basel, Switzerland) · 2024Review
- The Global Impact of COVID-19: A Comprehensive Analysis of Its Effects on Various Aspects of Life.Toxicology research · 2024Review
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
- Investigating the mode of transmission of COVID-19 through genital secretions, semen, the birth canal, and lactation: A systematic review.Journal of education and health promotion · 2024Article
- Female reproductive health during the COVID-19 pandemic: latest evidence and understanding.Archives of gynecology and obstetrics · 2023Review
- Effects of SARS-CoV-2 infection on embryological outcomes in assisted reproductive technology during the Omicron epidemic.Journal of ovarian research · 2023Article
- Maternal SARS-CoV-2 infection: The potential vertical transmission of SARS-CoV-2 and impact on neonates: A review.Pediatric discovery · 2023Review
- Investigation of Coronavirus disease 2019 virus in vaginal fluid and menses blood and the effect on menstrual cycle duration and sexual desire: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- The microbiota of pregnant women with SARS-CoV-2 and their infants.Microbiome · 2023Article
- COVID-19: the possibility, ways, mechanisms, and interruptions of mother-to-child transmission.Archives of gynecology and obstetrics · 2023Review
- Congenital SARS-CoV-2 Infection in Two Neonates with Confirmation by Viral Culture of the Placenta in One Case.Viruses · 2023Article
- SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study.JBRA assisted reproduction · 2023Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spread mainly through respiratory droplets or direct contact. However, the infection condition of the genital system is unknown. Our aim in this study was to determine if SARS-CoV-2 is present in the vaginal fluid of women with coronavirus disease 2019 (COVID-19).
methodsTen women with confirmed severe COVID-19 pneumonia admitted to the Tongji Zhongfa Hospital intensive care unit from 4 February 2020 through 24 February 2020 were included. Clinical records, laboratory results, and computed tomography examinations were retrospectively reviewed. The potential for genital infection was accessed by testing for the presence of SARS-CoV-2 in vaginal fluids obtained from vaginal swab samples. Reverse transcriptase polymerase chain reaction was used to confirm the SARS-CoV-2 infection in vaginal fluids.
resultsThe clinical characteristics of the 10 women were similar to those reported in other severe COVID-19 patients. All 10 patients were tested for SARS-CoV-2 in vaginal fluid, and all samples tested negative for the virus.
conclusionsFindings from this small group of cases suggest that SARS-CoV-2 virus does not exist in the vaginal fluids of severe COVID-19 patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.