Evidence map›Paper›PMID 32240719›Full record

Trial reportMedecine et maladies infectieuses2020

No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection.

J M Molina, C Delaugerre, J Le Goff, B Mela-Lima, D Ponscarme, L Goldwirt, N de Castro

Open access · bronzeAbstract readClinical TrialLetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medecine et maladies infectieuses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 425 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
425citing papers in PubMed, 12 pooled it
19.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

425 citing papers in PubMed, 12 syntheses or guidelines pooled it, 787 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Chloroquine or hydroxychloroquine for prevention and treatment of COVID-19.The Cochrane database of systematic reviews · 2021
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Is there any potential management against COVID-19? A systematic review and meta-analysis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2020
    Pooled it
  13. Trial
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

365 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J M MolinaInfectious Diseases Department, AP-HP-Saint-Louis Hospital, 1, avenue Claude-Vellefaux 75010 Paris, France; U944 INSERM, université de Paris, 75000 Paris, France. Electronic address: jean-michel.molina@aphp.fr.
C DelaugerreUniversité de Paris, 75000 Paris, France; Virology Department, AP-HP-Saint-Louis Hospital, 75010 Paris, France.
J Le GoffUniversité de Paris, 75000 Paris, France; Virology Department, AP-HP-Saint-Louis Hospital, 75010 Paris, France.
B Mela-LimaInfectious Diseases Department, AP-HP-Saint-Louis Hospital, 1, avenue Claude-Vellefaux 75010 Paris, France.
D PonscarmeInfectious Diseases Department, AP-HP-Saint-Louis Hospital, 1, avenue Claude-Vellefaux 75010 Paris, France.
L GoldwirtPharmacology Department, AP-HP, Saint-Louis Hospital, 75010 Paris, France.
N de CastroInfectious Diseases Department, AP-HP-Saint-Louis Hospital, 1, avenue Claude-Vellefaux 75010 Paris, France.
Hôpital Saint-Louis · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntiviral AgentsAzithromycinBetacoronavirusCoronavirus InfectionsCOVID-19Drug Therapy, CombinationFemaleHumansHydroxychloroquineMaleMiddle AgedPandemicsPneumonia, ViralSARS-CoV-2Antiviral AgentsAzithromycinHydroxychloroquine

Identifiers

PMID32240719
PMCPMC7195369
OpenAlexW3013899502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.