Evidence map›Paper›PMID 32240496›Full record

ArticleJournal of cardiovascular translational research2021

Low Wall Shear Stress Is Associated with Saphenous Vein Graft Stenosis in Patients with Coronary Artery Bypass Grafting.

Muhammad Owais Khan, Justin S Tran, Han Zhu, Jack Boyd, René R Sevag Packard, Ronald P Karlsberg, Andrew M Kahn, Alison L Marsden

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Impact of Graft Velocity on Saphenous Vein Graft Atherosclerosis after Coronary Artery Bypass Grafting.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2024
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. FSGe: A fast and strongly-coupled 3D fluid-solid-growth interaction method.Computer methods in applied mechanics and engineering · 2024
    Article
  8. Article
  9. Article
  10. Hemodynamics and Wall Mechanics of Vascular Graft Failure.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Muhammad Owais KhanDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Justin S TranDepartment of Mechanical Engineering, California State University Fullerton, Fullerton, CA, USA.
Han ZhuDepartment of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Jack BoydDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
René R Sevag PackardDepartment of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Ronald P KarlsbergCardiovascular Medical Group of Southern California, Beverly Hills, CA, USA.
Andrew M KahnDivision of Cardiovascular Medicine, University of California San Diego, La Jolla, CA, USA. akahn@ucsd.edu.
Alison L MarsdenDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. amarsden@stanford.edu.
Stanford University · USCalifornia State University, Fullerton · USCardiovascular Medical Group · USUniversity of California, Los Angeles · USUniversity of California, San Diego · US

Funding

Patient-specific thrombosis risk in atrial fibrillation by 4D CT imaging of atrial kinetics combined with computational fluid dynamicsR01HL160024 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEL ALAMO, JUAN CARLOS, KAHN, ANDREW · 2021 to 2024
$2.7M
Multiscale modeling for vein graft failure risk stratification in CABG patientsR01HL123689 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARSDEN, ALISON L · 2014 to 2018
$1.9M
Integrating 3-D Intravascular Sensors with Fractional Flow Reserve for Lipid-Rich PlaquesI01BX004558 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI PACKARD, RENE R.S. · 2020 to 2023
–
BLRD VA I01 BX004558NHLBI NIH HHS R01 HL123689NHLBI NIH HHS R01 HL160024
6 · The paper itself

Abstract

Biomechanical forces may play a key role in saphenous vein graft (SVG) disease after coronary artery bypass graft (CABG) surgery. Computed tomography angiography (CTA) of 430 post-CABG patients were evaluated and 15 patients were identified with both stenosed and healthy SVGs for paired analysis. The stenosis was virtually removed, and detailed 3D models were reconstructed to perform patient-specific computational fluid dynamic (CFD) simulations. Models were processed to compute anatomic parameters, and hemodynamic parameters such as local and vessel-averaged wall shear stress (WSS), normalized WSS (WSS

Indexed as

Coronary CirculationHemodynamicsAgedAged, 80 and overComputed Tomography AngiographyCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseCoronary VesselsFemaleGraft Occlusion, VascularHumansHydrodynamicsMaleMiddle AgedPatient-Specific ModelingComputational fluid dynamicsComputed tomography angiographyCoronary artery bypass graft surgerySaphenous vein graftWall shear stress

Identifiers

PMID32240496
PMCPMC7529767
OpenAlexW3015018148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.