ArticleEuropean child & adolescent psychiatry2021
Sustained remission of child depression despite drift in parent emotion management skills 18 weeks following Parent Child Interaction Therapy: emotion development.
Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Preadolescent Benefits of Parent-Child Interaction Therapy Emotion Development for Preschool Depression: 4-Year Follow-Up.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Trial
- Early Emotion Development Intervention Improves Mental Health Outcomes in Low-Income, High-Risk Community Children.Child psychiatry and human development · 2025Trial
- Sleep problems in preschool-onset major depressive disorder: the effect of treatment with parent-child interaction therapy-emotion development.European child & adolescent psychiatry · 2021Trial
- Changes in self-reported and observed parenting following a randomized control trial of parent-child interaction therapy for the treatment of preschool depression.Journal of child psychology and psychiatry, and allied disciplines · 2021Trial
- Characterizing Early Childhood Disruptive Mood Dysregulation Disorder.JAACAP open · 2026Article
- Preschool Mood Disorders: A Review of the Literature from 2017 to 2024.Child and adolescent psychiatric clinics of North America · 2025Review
- Preschool depression: clinical course, risk pathways, and early intervention strategies.Frontiers in psychiatry · 2025Review
- Novel mechanism-based treatments for pediatric anxiety and depressive disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Article
- Developmental pathways from preschool temper tantrums to later psychopathology.Development and psychopathology · 2023Article
- Scientific collaborations and research trends in Parent-Child Interaction Therapy: a bibliometric analysis.Frontiers in psychology · 2023Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Whether effects of psychotherapies for depression are sustained after treatment is an important clinical issue. In older depressed children and adolescents such treatments have been shown to be sustained for several months. Rates of remission ranged from 62-69% at 3 months-1 year in one large scale study. To date there has been no data to inform whether the effects of earlier interventions for depression in the preschool period are sustained. To address this, we used data from a randomized controlled trial of a novel early intervention for depression called "Parent Child Interaction Therapy Emotion Development" (PCIT-ED) that has shown efficacy for depression, parenting stress and parenting practices. Participants and their caregivers were re-assessed 18 weeks after treatment completion. All study procedures were approved by the Washington University School of Medicine Internal Review Board prior to data collection. Study findings demonstrated a high rate of sustained gains in remission from depression, decreased parenting stress and parental depression 18 weeks after completion of a trial of PCIT-ED in a population of young children. Parental response to the child expression of emotion, a key treatment target drifted back towards baseline after 3 months. Relapse rates were 17% and predictors of relapse were the presence of an externalizing disorder, a higher number of co-morbid disorders and poorer guilt reparation and emotion regulation measured at treatment completion. This extends the body of literature demonstrating parent-child interaction therapy (PCIT) to have sustained effects on targeted disruptive symptom profiles to early childhood depression. This relatively low relapse rate after 18 weeks is comparable or better than many empirically proven treatments for depression in older children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.