Evidence map›Paper›PMID 32240370›Full record

ArticleEuropean child & adolescent psychiatry2021

Sustained remission of child depression despite drift in parent emotion management skills 18 weeks following Parent Child Interaction Therapy: emotion development.

Joan Luby, Meghan Rose Donohue, Kirsten Gilbert, Rebecca Tillman, Deanna M Barch

Open access · greenAbstract read
In one paragraph

Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Preschool Mood Disorders: A Review of the Literature from 2017 to 2024.Child and adolescent psychiatric clinics of North America · 2025
    Review
  7. Review
  8. Novel mechanism-based treatments for pediatric anxiety and depressive disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joan LubyWashington University School of Medicine, Child Psychiatry, St. Louis, MO, 63130, USA. lubyj@wustl.edu.ORCID http://orcid.org/0000-0001-5352-1721
Meghan Rose DonohueWashington University School of Medicine, Child Psychiatry, St. Louis, MO, 63130, USA.
Kirsten GilbertWashington University School of Medicine, Child Psychiatry, St. Louis, MO, 63130, USA.
Rebecca TillmanWashington University School of Medicine, Child Psychiatry, St. Louis, MO, 63130, USA.
Deanna M BarchDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Washington University in St. Louis · US

Funding

Developmental Neuroscience and Child PsychopathologyT32MH100019 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, JOAN L. LUBY · 2013 to 2026
$4.8M
A RANDOMIZED CONTROLLED TRIAL OF PCIT-ED FOR PRESCHOOL DEPRESSIONR01MH098454 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA, LUBY, JOAN L. · 2013 to 2017
$4.6M
Neurodevelopmental Emergence of Callous-Unemotional Behavior Beginning in Infancy: Neural Markers and Environmental Risk and Protective FactorsK23MH125023 · NIMH · WASHINGTON UNIVERSITY · PI DONOHUE, MEGHAN ROSE · 2021 to 2025
$904k
Heightened Performance Monitoring and Overcontrol: Neural Markers and Caregiving Processes in Developmental Risk TrajectoriesK23MH115074 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN · 2017 to 2021
$821k
NIMH NIH HHS 5R01MH098454-02NIMH NIH HHS K23 MH115074NIMH NIH HHS K23 MH125023NIMH NIH HHS R01 MH098454NIMH NIH HHS T32 MH100019
6 · The paper itself

Abstract

Whether effects of psychotherapies for depression are sustained after treatment is an important clinical issue. In older depressed children and adolescents such treatments have been shown to be sustained for several months. Rates of remission ranged from 62-69% at 3 months-1 year in one large scale study. To date there has been no data to inform whether the effects of earlier interventions for depression in the preschool period are sustained. To address this, we used data from a randomized controlled trial of a novel early intervention for depression called "Parent Child Interaction Therapy Emotion Development" (PCIT-ED) that has shown efficacy for depression, parenting stress and parenting practices. Participants and their caregivers were re-assessed 18 weeks after treatment completion. All study procedures were approved by the Washington University School of Medicine Internal Review Board prior to data collection. Study findings demonstrated a high rate of sustained gains in remission from depression, decreased parenting stress and parental depression 18 weeks after completion of a trial of PCIT-ED in a population of young children. Parental response to the child expression of emotion, a key treatment target drifted back towards baseline after 3 months. Relapse rates were 17% and predictors of relapse were the presence of an externalizing disorder, a higher number of co-morbid disorders and poorer guilt reparation and emotion regulation measured at treatment completion. This extends the body of literature demonstrating parent-child interaction therapy (PCIT) to have sustained effects on targeted disruptive symptom profiles to early childhood depression. This relatively low relapse rate after 18 weeks is comparable or better than many empirically proven treatments for depression in older children.

Indexed as

Parent-Child RelationsChild, PreschoolDepressionEmotionsFemaleHumansMalePsychometricsPsychotherapyTime FactorsChildhood depressionChild psychopathologyParentingPCIT

Identifiers

PMID32240370
PMCPMC7529941
OpenAlexW3014788372

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.