Evidence map›Paper›PMID 32240093›Full record

ArticleeLife2020

Cell-type diversity and regionalized gene expression in the planarian intestine.

David J Forsthoefel, Nicholas I Cejda, Umair W Khan, Phillip A Newmark

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

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  16. Review
  17. A Planarian Model System to Study Host-Pathogen Interactions.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David J ForsthoefelGenes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, United States.ORCID 0000-0002-8583-4383
Nicholas I CejdaGenes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, United States.ORCID 0000-0003-4518-4125
Umair W KhanHoward Hughes Medical Institute, Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, United States.ORCID 0000-0003-0206-0667
Phillip A NewmarkHoward Hughes Medical Institute, Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, United States.ORCID 0000-0003-0793-022X
Howard Hughes Medical Institute · USOklahoma Medical Research Foundation · US

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Wade Williams · 2018 to 2026
$27.1M
Understanding connective tissue development and disease with PDGFR-driven..... P20GM103636 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI THOMPSON, LINDA F · 2013 to 2023
$26.9M
TUMOR RESISTANCE MECHANISMS TO ANTI-VEGF THERAPY IN PROSTATE CANCER (Sukyung Woo)P20GM103639 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI DHANASEKARAN, DANNY N. · 2012 to 2022
$21.3M
Quantitative Analysis Core P30GM110766 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI GAFFNEY, PATRICK M · 2014 to 2018
$6.1M
Stem cell proliferation and differentiation in planariaR01HD043403 · NICHD · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Phillip A Newmark · 2003 to 2026
$5.1M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA225520NICHD NIH HHS R01 HD043403NIGMS NIH HHS COBRE GM103636-Project 1NIGMS NIH HHS P20 GM103636NIGMS NIH HHS P20 GM103639NIGMS NIH HHS P30 GM110766
6 · The paper itself

Abstract

Proper function and repair of the digestive system are vital to most animals. Deciphering the mechanisms involved in these processes requires an atlas of gene expression and cell types. Here, we applied laser-capture microdissection (LCM) and RNA-seq to characterize the intestinal transcriptome of

Indexed as

AnimalsGene ExpressionHedgehog ProteinsHumansIntestinesPlanariansRegenerationSignal TransductionTranscription FactorsTranscriptomeHedgehog ProteinsTranscription Factorsdigestive systemgeneticsgenomicsintestinelaser-capture microdissectionplanarianregenerationregenerative medicinestem cells

Identifiers

PMID32240093
PMCPMC7117911
OpenAlexW3014201892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.