Evidence map›Paper›PMID 32240015›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020

Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice.

Kelly N Z Fuller, Colin S McCoin, Julie Allen, Shelby Bell-Glenn, Devin C Koestler, Gerald W Dorn, John P Thyfault

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Loss of ovarian function prevents exercise-induced activation of hepatic mitophagic flux.American journal of physiology. Endocrinology and metabolism · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Exercise during weight loss improves hepatic mitophagy.Sports medicine and health science · 2022
    Article
  8. Article
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  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kelly N Z FullerDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0002-9335-9316
Colin S McCoinDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0002-8557-6441
Julie AllenDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas.
Shelby Bell-GlennDepartment of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, Kansas.
Devin C KoestlerDepartment of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, Kansas.
Gerald W DornCenter for Pharmacogenomics, Department of Internal Medicine, Washington University, School of Medicine, St. Louis, Missouri.
John P ThyfaultDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas.
University of Kansas Medical Center · USVeterans Health Administration · USWashington University in St. Louis · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Using Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Kalyani Pyaram, Steven Allan Soper · 2019 to 2026
$21.5M
THE MITOCHONDRIAL DYNAMISM/FITNESS/BIOGENESIS INTERACTOME IN CARDIAC DISEASER35HL135736 · NHLBI · WASHINGTON UNIVERSITY · PI DORN, GERALD W. · 2017 to 2023
$6.4M
Using PCORnet to Expand the DS-CONNECT Cohort Through Healthcare System Recruitment, Incorporating Electronic Health Records, and Assessing Self-DeterminationU54HD090216 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI COLOMBO, JOHN A. · 2016 to 2020
$6.2M
NRSA Training CoreTL1TR002368 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jennifer Lynn Goldman, NICOLE L NOLLEN · 2017 to 2026
$4.0M
Divergence in Aerobic Capacity Drives Liver and Brain HealthR01DK121497 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI THYFAULT, JOHN P · 2019 to 2022
$2.2M
Sexual dimorphism, hepatic mitochondrial adaptations, and hepatic steatosisI01BX002567 · VA · KANSAS CITY VA MEDICAL CENTER · PI THYFAULT, JOHN P · 2015 to 2025
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BLRD VA I01 BX002567NCATS NIH HHS TL1 TR002368NHLBI NIH HHS R35 HL135736NICHD NIH HHS U54 HD090216NIDDK NIH HHS R01 DK121497NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM130423
6 · The paper itself

Abstract

Both lipid oversupply and poor mitochondrial function (low respiration and elevated H

Indexed as

Fatty LiverHydrogen PeroxideMembrane ProteinsMitochondrial ProteinsSex FactorsAnimalsDiet, High-FatFemaleGenotypeLipidsLiverMaleMiceMice, Inbred C57BLMice, KnockoutBNip3 protein, mouseHydrogen PeroxideLipidsMembrane ProteinsMitochondrial ProteinslivermetabolismNAFLDreactive oxygen species

Identifiers

PMID32240015
PMCPMC7272752
OpenAlexW3014808028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.