Evidence map›Paper›PMID 32239615›Full record

ArticleMolecular oncology2020

Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.

Henrike K Grosshans, Tom T Fischer, Julia A Steinle, Allison L Brill, Barbara E Ehrlich

Open access · goldAbstract read
In one paragraph

Article in Molecular oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. New Insights into the Regulation of mTOR Signaling via CaInternational journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Neuronal calcium sensor 1 (NCS1) dependent modulation of neuronal morphology and development.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Henrike K GrosshansDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Tom T FischerDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-2138-9102
Julia A SteinleDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Allison L BrillDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5046-3578
Barbara E EhrlichDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9657-9704
Yale University · USHeidelberg University · DE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1M
Translational CoreP01DK057751 · NIDDK · YALE UNIVERSITY · PI YANG, XIAOYONG · 2001 to 2020
$25.6M
INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32GM007324 · NIGMS · YALE UNIVERSITY · PI BENNETT, ANTON M · 1987 to 2022
$6.2M
Dual-specificity phosphatase action in muscle diseaseR01AR080152 · NIAMS · YALE UNIVERSITY · PI Anton M Bennett · 2022 to 2026
$2.5M
A super-resolution microscope for research and educationS10OD020142 · OD · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2015 to 2015
$600k
Investigating Polycystin-2 up-regulation as a stress response through its role in non-alcoholic fatty liver diseaseF31DK118836 · NIDDK · YALE UNIVERSITY · PI BRILL, ALLISON LEIGH · 2019 to 2020
$76k
NCATS NIH HHS UL1 TR001863NIAMS NIH HHS R01 AR080152NIDDK NIH HHS F31 DK118836NIDDK NIH HHS P01 DK057751NIDDK NIH HHS P30 DK034989NIGMS NIH HHS T32 GM007324NIH HHS S10 OD020142
6 · The paper itself

Abstract

Changes in intracellular calcium (Ca

Indexed as

Base SequenceCalciumCell Line, TumorCell MovementCell SurvivalChelating AgentsCRISPR-Cas SystemsCytosolEndoplasmic ReticulumGene Expression Regulation, NeoplasticHumansInositol 1,4,5-Trisphosphate ReceptorsNeoplasmsNeuronal Calcium-Sensor ProteinsNeuropeptidesNF-kappa BCalciumChelating Agentsfrequenin calcium sensor proteinsInositol 1,4,5-Trisphosphate ReceptorsNeuronal Calcium-Sensor ProteinsNeuropeptidesNF-kappa BProto-Oncogene Proteins c-aktTumor Necrosis Factor-alphaCa2+ binding proteinCa2+ signalingNFκBPKB/Akttumor progression

Identifiers

PMID32239615
PMCPMC7266285
OpenAlexW3014882372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.