Evidence map›Paper›PMID 32239144›Full record

ArticleThe international journal of neuropsychopharmacology2020

Current and Novel Approaches to Mitigate Cardiometabolic Adverse Effects of Second-Generation Antipsychotics.

Karolina Skonieczna-Żydecka, Igor Łoniewski, Ewa Stachowska, Wojciech Marlicz, Christoph U Correll

Open access · goldAbstract read
In one paragraph

Article in The international journal of neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Karolina Skonieczna-ŻydeckaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland.
Igor ŁoniewskiDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland.
Ewa StachowskaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland.
Wojciech MarliczDepartment of Gastroenterology, Pomeranian Medical University, Szczecin, Poland.
Christoph U CorrellDepartment of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.
Pomeranian Medical University · PLNorthwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Second-generation antipsychotic-related weight gain and metabolic disturbances are a major public health issue given the widespread prescribing of these medications. The lack of clearly known mechanisms of cardiometabolic adverse effects and the relevance of cardiometabolic health for survival make this an important area for research. While nonpharmacologic and some pharmacologic treatments have shown benefits vs control conditions or placebo, the effects are modest and long-term benefits are less clear. Therefore, new approaches to mitigate second-generation antipsychotic-associated cardiometabolic burden are sorely needed.

Indexed as

Risk Reduction BehaviorAnimalsAnti-Obesity AgentsAntipsychotic AgentsCardiometabolic Risk FactorsCardiovascular DiseasesDysbiosisGastrointestinal MicrobiomeHumansMetabolic DiseasesPrognosisRecombinant Fusion ProteinsRisk AssessmentAnti-Obesity AgentsAntipsychotic AgentsRecombinant Fusion ProteinsTat-3L4F peptidecardiometabolic riskgut microbiotasecond-generation antipsychoticsTat-3L4F

Identifiers

PMID32239144
PMCPMC7689205
OpenAlexW3015057866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.