Evidence map›Paper›PMID 32239126›Full record

ArticleBioinformatics (Oxford, England)2020

EVICAN-a balanced dataset for algorithm development in cell and nucleus segmentation.

Mischa Schwendy, Ronald E Unger, Sapun H Parekh

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

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0cells of the map it votes in
21citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Mischa SchwendyMax Planck Institute for Polymer Research, Mainz 55128, Germany.
Ronald E UngerInstitute of Pathology, Universitätsmedizin-Mainz, Mainz 55131, Germany.
Sapun H ParekhMax Planck Institute for Polymer Research, Mainz 55128, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationDeep learning use for quantitative image analysis is exponentially increasing. However, training accurate, widely deployable deep learning algorithms requires a plethora of annotated (ground truth) data. Image collections must contain not only thousands of images to provide sufficient example objects (i.e. cells), but also contain an adequate degree of image heterogeneity.

resultsWe present a new dataset, EVICAN-Expert visual cell annotation, comprising partially annotated grayscale images of 30 different cell lines from multiple microscopes, contrast mechanisms and magnifications that is readily usable as training data for computer vision applications. With 4600 images and ∼26 000 segmented cells, our collection offers an unparalleled heterogeneous training dataset for cell biology deep learning application development. AVAILABILITY AND IMPLEMENTATION: The dataset is freely available (https://edmond.mpdl.mpg.de/imeji/collection/l45s16atmi6Aa4sI?q=). Using a Mask R-CNN implementation, we demonstrate automated segmentation of cells and nuclei from brightfield images with a mean average precision of 61.6 % at a Jaccard Index above 0.5.

Indexed as

AlgorithmsCell NucleusImage Processing, Computer-AssistedMicroscopy

Identifiers

PMID32239126
PMCPMC7320615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.