Evidence map›Paper›PMID 32238924›Full record

ArticleNature2020

U1 snRNP regulates chromatin retention of noncoding RNAs.

Yafei Yin, J Yuyang Lu, Xuechun Zhang, Wen Shao, Yanhui Xu, Pan Li, Yantao Hong, Li Cui, Ge Shan, Bin Tian and 2 more

Abstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 1 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 1 synthesis or guideline pooled it, 239 citations in OpenAlex.

  1. Pooled it
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  17. High-throughput Screening of Sequence Elements Associated with RNA Localization.Computational and structural biotechnology journal · 2026
    Article
  18. Review
  19. Article
  20. Article

76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yafei YinTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China. yafei@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-0171-844X
J Yuyang LuTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Xuechun ZhangTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Wen ShaoTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Yanhui XuTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Pan LiTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Yantao HongTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Li CuiTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.
Ge ShanSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui Province, China.ORCID http://orcid.org/0000-0002-3561-2088
Bin TianDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School and Rutgers Cancer Institute of New Jersey, Newark, NJ, USA.ORCID http://orcid.org/0000-0001-8903-8256
Qiangfeng Cliff ZhangTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.ORCID http://orcid.org/0000-0002-4913-0338
Xiaohua ShenTsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China. xshen@tsinghua.edu.cn.
Center for Life Sciences · CNKing Center · USRutgers, The State University of New Jersey · USUniversity of Science and Technology of China · CN

Funding

Regulation of Alternative Cleavage and PolyadenylationR01GM084089 · NIGMS · WISTAR INSTITUTE · PI TIAN, BIN · 2008 to 2023
$6.7M
NIGMS NIH HHS R01 GM084089
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) and promoter- or enhancer-associated unstable transcripts locate preferentially to chromatin, where some regulate chromatin structure, transcription and RNA processing

Indexed as

Transcription, GeneticAnimalsCell LineChromatinHigh-Throughput Nucleotide SequencingHumansMiceMouse Embryonic Stem CellsMutagenesisNucleotide MotifsRibonucleoprotein, U1 Small NuclearRNA, Long NoncodingRNA Polymerase IIRNA PrecursorsRNA, Small NuclearRNA Splice SitesChromatinRibonucleoprotein, U1 Small NuclearRNA, Long NoncodingRNA Polymerase IIRNA PrecursorsRNA, Small NuclearRNA Splice SitesSNRNP70 protein, humanU1 small nuclear RNA

Identifiers

PMID32238924
PMCPMC12018070
OpenAlexW3011709397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.