ArticleThe ISME journal2020
A role for gut microbiota in host niche differentiation.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- Fecal Pathogenic Bacteria Composition and Community Assembly Mechanisms in Captive Brown Bears and Asiatic Black Bears.Animals : an open access journal from MDPI · 2026Article
- Sympatric Speciation of Tibetan Loaches (Ecology and evolution · 2026Article
- Comparative analysis of morphology and gut microbiome underlying trophic niche differentiation in three stomatopod species.BMC microbiology · 2026Article
- Characteristics comparative of gut microbiota in four small mammal species co-occurring in the Hengduan Mountains: differences in environmental adaptation strategies between alien and endemic species.BMC microbiology · 2026Article
- Niche specialization and cross-feeding interactions shaping gut microbial fiber degradation in a model omnivore.bioRxiv : the preprint server for biology · 2026Article
- Phylosymbiosis and functional redundancy in the Drosophila (Diptera: Drosophilidae) gut microbiome and its implications for host fitness.Journal of insect science (Online) · 2026Article
- Dietary niche partitioning and convergent gut microbiota in sympatricFrontiers in microbiology · 2026Article
- Comprehensive Phylogenomic Analyses Support the Reclassification of Multiple Bacteroides Species.Current microbiology · 2025Article
- Review
- Gut microbiome and diet contribute to ecological niche differentiation between argali (Ovis ammon hodgsoni) and blue sheep (Pseudois nayaur) on the Qinghai-Tibet Plateau.Communications biology · 2025Article
- The gut microbiome of Madagascar's lemurs from forest fragments in the central highlands.Primates; journal of primatology · 2025Article
- Captive environments reshape the compositions of carbohydrate active enzymes and virulence factors in wolf gut microbiome.BMC microbiology · 2025Article
- Why Didn't the Sifaka Cross the Road? Divergence of Propithecus edwardsi Gut Microbiomes Across Geographic Barriers in Ranomafana National Park, Madagascar.American journal of primatology · 2025Article
- Gut microbiota profiles of sympatric snub-nosed monkeys and macaques in Qinghai-Tibetan Plateau show influence of phylogeny over diet.Communications biology · 2025Article
- Bacterial transmission within social groups shapes the underexplored gut microbiome in the lemur Indri indri.The ISME journal · 2025Article
- Ecological and evolutionary responses of earthworm holobionts to environmental changes.The ISME journal · 2025Review
- Geographical Differences and Temporal Dynamics of Intestinal Microbiota in Endangered Great BustardInternational journal of microbiology · 2025Article
- From leaves to microbes: How diet and season shape the fecal microbiome of captive Coquerel´s Sifakas (Frontiers in microbiomes · 2025Article
- The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change.Animal microbiome · 2024Article
- Comparative analysis of gut microbiota of Chinese Kunming dog, German Shepherd dog, and Belgian Malinois dog.Journal of veterinary science · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
If gut microbes influence host behavioral ecology in the short term, over evolutionary time, they could drive host niche differentiation. We explored this possibility by comparing the gut microbiota of Madagascar's folivorous lemurs from Indriidae and Lepilemuridae. Occurring sympatrically in the eastern rainforest, our four, target species have different dietary specializations, including frugo-folivory (sifakas), young-leaf folivory (indri and woolly lemurs), and mature-leaf folivory (sportive lemurs). We collected fecal samples, from 2013 to 2017, and used amplicon sequencing, metagenomic sequencing, and nuclear magnetic resonance spectroscopy, respectively, to integrate analyses of gut microbiome structure and function with analysis of the colonic metabolome. The lemurs harbored species-specific microbiomes, metagenomes, and metabolomes that were tuned to their dietary specializations: Frugo-folivores had greater microbial and metagenomic diversity, and harbored generalist taxa. Mature-leaf folivores had greater individual microbiome variation, and taxa and metabolites putatively involved in cellulolysis. The consortia even differed between related, young-leaf specialists, with indri prioritizing metabolism of fiber and plant secondary compounds, and woolly lemurs prioritizing amino-acid cycling. Specialized gut microbiota and associated gastrointestinal morphologies enable folivores to variably tolerate resource fluctuation and support nutrient extraction from challenging resources (e.g., by metabolizing plant secondary compounds or recalcitrant fibers), perhaps ultimately facilitating host species' diversity and specialized feeding ecologies.
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