Evidence map›Paper›PMID 32238779›Full record

ArticleJournal of microbiology and biotechnology2020

Melanin Bleaching and Melanogenesis Inhibition Effects of

Sukyung Kim, Hoonhee Seo, Hafij Al Mahmud, Md Imtiazul Islam, Omme Fatema Sultana, Youngkyoung Lee, Minhee Kim, Ho-Yeon Song

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Dismantling darkness: interdisciplinary perspectives on melanin degradation.World journal of microbiology & biotechnology · 2026
    Review
  2. Article
  3. Postbiotic Effects ofMicroorganisms · 2025
    Article
  4. Mutagenicity and Genotoxicity Assessment ofJournal of microbiology and biotechnology · 2024
    Article
  5. Skin Deep: The Potential of Microbiome Cosmetics.Journal of microbiology (Seoul, Korea) · 2024
    Review
  6. Applications of Probiotic Constituents in Cosmetics.Molecules (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Biodegradation and Removal of PAHs byJournal of microbiology and biotechnology · 2021
    Article
  9. The Biotechnological Potential ofFoods (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sukyung KimDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Hoonhee SeoDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Hafij Al MahmudDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Md Imtiazul IslamDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Omme Fatema SultanaDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Youngkyoung LeeDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.
Minhee KimEmory university, Institute for Quantitative Theory and Methods (QuanTM), GA 30322, USA.
Ho-Yeon SongDepartment of Microbiology and Immunology, School of Medicine, Soonchunhyang University, Cheonan 31151, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overproduction and accumulation of melanin in the skin will darken the skin and cause skin disorders. So far, components that can inhibit tyrosinase, a melanin synthase of melanocytes, have been developed and used as ingredients of cosmetics or pharmaceutical products. However, most of existing substances can only inhibit the biosynthesis of melanin while melanin that is already synthesized and deposited is not directly decomposed. Thus, their effects in decreasing melanin concentration in the skin are weak. To overcome the limitation of existing therapeutic agents, we started to develop a substance that could directly biodegrade melanin. We screened traditional fermented food microorganisms for their abilities to direct biodegrade melanin. As a result, we found that a kimchi-derived

Indexed as

Cell SurvivalFermented FoodsMelaninsMelanocytesMonophenol MonooxygenasePediococcus acidilacticiPerillaPhylogenyPlant LeavesRepublic of KoreaRNA, Ribosomal, 16SMelaninsMonophenol MonooxygenaseRNA, Ribosomal, 16SmelaninPediococcus acidilactici PMC48perilla leaf kimchityrosinase

Identifiers

PMID32238779
PMCPMC9728375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.