Evidence map›Paper›PMID 32238722›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6β-iodomethyl-norcholesterol Scintigraphy.

Seisuke Sato, Hitomi Imachi, Toshihiro Kobayashi, Kensaku Fukunaga, Jingya Lyu, Tao Dong, Yuuki Yoshioka, Takanobu Saheki, Youko Fukata, Natsuki Ban and 3 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Co-Existing Ectopic Cortisol-Producing Adenoma and Retroperitoneal Schwannoma, a Rare Case Report.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Seisuke SatoDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Hitomi ImachiDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Toshihiro KobayashiDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Kensaku FukunagaDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Jingya LyuDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Tao DongDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Yuuki YoshiokaDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Takanobu SahekiDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Youko FukataDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Natsuki BanDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Kurumi UrushiharaDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Kyuuichi KadotaDepartment of Pathology, Faculty of Medicine, Kagawa University, Japan.
Koji MuraoDepartment of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Japan.
Kagawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 50-year-old man was referred to our department for overt Cushing's syndrome (CS). His plasma cortisol concentrations were 314 μg/L, and his urinary cortisol concentrations were 431 μg/day. The plasma adrenocorticotropic hormone (ACTH) concentration was below the detectable limit. Computed tomography revealed atrophy of both adrenal glands and the presence of a left pararenal tumor. 131I-6β-iodomethyl-norcholesterol scintigraphy showed an intense uptake by the left pararenal tumor. These findings suggested that the left pararenal tumor was ectopic cortisol-producing adrenocortical adenoma. This case serves as a reminder that 131I-6β-iodomethyl-norcholesterol scintigraphy is an effective method for diagnosing ACTH-independent CS in which no adrenal tumor has been found.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical AdenomaAdrenocorticotropic HormoneCushing SyndromeHumansHydrocortisoneIodine RadioisotopesMaleMiddle AgedRadionuclide ImagingAdrenocorticotropic HormoneHydrocortisoneIodine Radioisotopescortisol-producing adrenocortical adenomasCushing's syndromeectopic adrenocortical adenomascintigraphy

Identifiers

PMID32238722
PMCPMC7434542
OpenAlexW3014664075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.