Evidence map›Paper›PMID 32238449›Full record

ArticleGenes & development2020

Blunting senescence boosts liver regeneration.

Jodie Birch, Jesus Gil

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jodie BirchMRC London Institute of Medical Sciences, London W12 0NN, United Kingdom.
Jesus GilMRC London Institute of Medical Sciences, London W12 0NN, United Kingdom.ORCID 0000-0002-4303-6260
NIHR Imperial Biomedical Research Centre · GB

Funding

Medical Research Council MC_U120085810
6 · The paper itself

Abstract

The mammalian liver possesses a unique capacity for regeneration. However, this regenerative potential declines with age due to unknown mechanisms. In this issue of

Indexed as

HepatectomyLiver RegenerationAnimalsHepatocytesLiverMiceABT-737aginghepatocyteliver regenerationp16Ink4ap21senescencesenolytic

Identifiers

PMID32238449
PMCPMC7111267
OpenAlexW3014921753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.